Importance of exercise immunology in health promotion

Autor(es)

Rosa Neto, J. C. ^[1] ; Lira, F. S. ^[1] ; de Mello, M. T. ^[2] ; Santos, Ronaldo Vagner T. ^{[2, 3, 4]}

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Paulo, Dept Nutr, Sao Paulo - Brazil

^[2] Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo - Brazil

^[3] UNIFESP Baixada Santista, Dept Ciencias Saude, BR-04020050 Sao Paulo - Brazil

^[4] Univ Sao Paulo, Dept Biosci, Sao Paulo - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: Amino Acids; v. 41, n. 5, p. 1165-1172, NOV 2011.
• Citações Web of Science: 23

Resumo

Chronic physical exercise with adequate intensity and volume associated with sufficient recovery promotes adaptations in several physiological systems. While intense and exhaustive exercise is considered an important immunosuppressor agent and increases the incidence of upper respiratory tract infections (URTI), moderate regular exercise has been associated with significant disease protection and is a complementary treatment of many chronic diseases. The effects of chronic exercise occur because physical training can induce several physiological, biochemical and psychological adaptations. More recently, the effect of acute exercise and training on the immunological system has been discussed, and many studies suggest the importance of the immune system in prevention and partial recovery in pathophysiological situations. Currently, there are two important hypotheses that may explain the effects of exercise and training on the immune system. These hypotheses including (1) the effect of exercise upon hormones and cytokines (2) because exercise can modulate glutamine concentration. In this review, we discuss the hypothesis that exercise may modulate immune functions and the importance of exercise immunology in respect to chronic illnesses, chronic heart failure, malnutrition and inflammation. (AU)

• Processo FAPESP: 07/00073-7 - Estudo do papel das citocinas pro-inflamatorias sobre o metabolismo de glutamina e glicose e a funcao de celulas do sistema imune em adultos treinados.
• Beneficiário: Ronaldo Vagner Thomatieli dos Santos
• Modalidade de apoio: Auxílio à Pesquisa - Regular