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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Importance of exercise immunology in health promotion

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Author(s):
Rosa Neto, J. C. [1] ; Lira, F. S. [1] ; de Mello, M. T. [2] ; Santos, Ronaldo Vagner T. [2, 3, 4]
Total Authors: 4
Affiliation:
[1] Univ Fed Sao Paulo, Dept Nutr, Sao Paulo - Brazil
[2] Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo - Brazil
[3] UNIFESP Baixada Santista, Dept Ciencias Saude, BR-04020050 Sao Paulo - Brazil
[4] Univ Sao Paulo, Dept Biosci, Sao Paulo - Brazil
Total Affiliations: 4
Document type: Review article
Source: Amino Acids; v. 41, n. 5, p. 1165-1172, NOV 2011.
Web of Science Citations: 23
Abstract

Chronic physical exercise with adequate intensity and volume associated with sufficient recovery promotes adaptations in several physiological systems. While intense and exhaustive exercise is considered an important immunosuppressor agent and increases the incidence of upper respiratory tract infections (URTI), moderate regular exercise has been associated with significant disease protection and is a complementary treatment of many chronic diseases. The effects of chronic exercise occur because physical training can induce several physiological, biochemical and psychological adaptations. More recently, the effect of acute exercise and training on the immunological system has been discussed, and many studies suggest the importance of the immune system in prevention and partial recovery in pathophysiological situations. Currently, there are two important hypotheses that may explain the effects of exercise and training on the immune system. These hypotheses including (1) the effect of exercise upon hormones and cytokines (2) because exercise can modulate glutamine concentration. In this review, we discuss the hypothesis that exercise may modulate immune functions and the importance of exercise immunology in respect to chronic illnesses, chronic heart failure, malnutrition and inflammation. (AU)