Loss of interest, depressed mood and impact on the quality of life: Cross-sectional survey

Autor(es)

Guajardo, Valeri D. ^[1] ; Souza, Bruno P. F. ^[1] ; Henriques, Sergio G. ^[1] ; Lucia, Mara C. S. ^[2] ; Menezes, Paulo R. ^[3] ; Martins, Milton A. ^[4] ; Tardivo, Leila S. L. P. C. ^[5] ; Gattaz, Wagner F. ^[1] ; Fraguas, Renerio ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Med, Clin Hosp, Inst Psychiat, Dept Psychiat, BR-05403010 Sao Paulo - Brazil

^[2] Univ Sao Paulo, Fac Med, Clin Hosp, Cent Inst, Div Psychol, BR-05403000 Sao Paulo - Brazil

^[3] Univ Sao Paulo, Fac Med, Dept Prevent Med, BR-01246903 Sao Paulo - Brazil

^[4] Univ Sao Paulo, Fac Med, Dept Clin Med, BR-01246903 Sao Paulo - Brazil

^[5] Univ Sao Paulo, Inst Psychol, Dept Clin Psychol, BR-05508030 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: BMC PUBLIC HEALTH; v. 11, OCT 25 2011.
• Citações Web of Science: 4
• Assunto(s): Transtornos mentais Doença crônica

Resumo

Background: Depressive symptoms and chronic disease have adverse effects on patients' health-related quality of life (H-RQOL). However, little is known about this effect on H-RQOL when only the two core depressive symptoms - loss of interest and depressed mood - are considered. The objective of this study is to investigate H-RQOL in the presence of loss of interest and depressed mood at a general medical outpatient unit. Methods: We evaluated 553 patients at their first attendance at a general medical outpatient unit of a teaching hospital. H-RQOL was assessed with the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36). Depressed mood and loss of interest were assessed by the Primary Care Evaluation of Mental Disorders (PRIME-MD)Patient Questionnaire. A physician performed the diagnosis of chronic diseases by clinical judgment and classified them in 13 possible pre-defined categories. We used multiple linear regression to investigate associations between each domain of H-RQOL and our two core depression symptoms. The presence of chronic diseases and demographic variables were included in the models as covariates. Results: Among the 553 patients, 70.5% were women with a mean age of 41.0 years (range 18-85, SD +/- 15.4). Loss of interest was reported by 54.6%, and depressed mood by 59.7% of the patients. At least one chronic disease was diagnosed in 59.5% of patients; cardiovascular disease was the most prevalent, affecting 20.6% of our patients. Loss of interest and depressed mood was significantly associated with decreased scores in all domains of H-RQOL after adjustment for possible confounders. The presence of any chronic disease was associated with a decrease in the domain of vitality. The analysis of each individual chronic disease category revealed that no category was associated with a decrease in more than one domain of H-RQOL. Conclusion: Loss of interest and depressed mood were associated with significant decreases in H-RQOL. We recommend these simple tests for screening in general practice. (AU)

• Processo FAPESP: 99/00669-9 - Utilizacao do prime-md por medicos nao psiquiatras para deteccao de depressao em ambulatorio de clinica medica.
• Beneficiário: Renério Fráguas Junior
• Modalidade de apoio: Auxílio à Pesquisa - Regular