Overview of Pectin-Derived Microparticles through Microfluidic Technology

Autor(es)

da Silva, Pedro Brivaldo Viana ; Fabi, Joao Paulo

• Tipo de documento: Artigo Científico
• Fonte: FLUIDS; v. 9, n. 8, p. 19-pg., 2024-08-01.

Resumo

The scientific field of microcarrier systems has gained significant advancements, especially in drug delivery and controlled release mechanisms. This manuscript provides a comprehensive overview of the progress in developing pectin-derived microcarriers fabricated using microfluidic technology. Pectin, a naturally occurring polysaccharide, has garnered attention due to its biocompatibility, biodegradability, and ability to form hydrogels, making it an ideal candidate for forming microcarriers. The integration of microfluidic technology in synthesizing these carriers has revolutionized their design and functionality, enabling precise control over size, morphology, and encapsulation efficiency. This review systematically analyzes the methodologies employed in the microfluidic fabrication of pectin-based microparticles, highlighting the significant advantages this technology offers, such as reduced use of solvents, enhanced reproducibility, and scalability. (AU)

• Processo FAPESP: 13/07914-8 - FoRC - Centro de Pesquisa em Alimentos
• Beneficiário: Bernadette Dora Gombossy de Melo Franco
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs
• Processo FAPESP: 22/12834-2 - Efeitos das pectinas modificadas na saúde intestinal: estudos pré-clínicos e clínicos para avaliar efeitos celulares, transcricionais e epigenéticos
• Beneficiário: Joao Paulo Fabi
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 22/12270-1 - Estudo da modulação da microbiota do cólon por meio de oligômeros de pectinas encapsulados em matriz péctica
• Beneficiário: Pedro Brivaldo Viana da Silva
• Modalidade de apoio: Bolsas no Brasil - Doutorado