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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Iron deficiency anaemia and blood lead concentrations in Brazilian children

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Autor(es):
Carvalho Rondo, Patricia Helen [1] ; Conde, Andreia [1] ; Souza, Miriam Coelho [2] ; Sakuma, Alice [3]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Sch Publ Hlth, Dept Nutr, Sao Paulo, SP - Brazil
[2] Methodist Univ, Fac Nutr, Piracicaba, SP - Brazil
[3] Adolfo Lutz Inst, Sao Paulo - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: Transactions of the Royal Society of Tropical Medicine and Hygiene; v. 105, n. 9, p. 525-530, SEP 2011.
Citações Web of Science: 6
Resumo

This study investigated the relationship between iron deficiency/iron deficiency anaemia, assessed by several parameters, and blood lead concentration in children. This cross-sectional study involved 384 Brazilian children, aged 2-11 years, who lived near a lead-manipulating industry. Complete blood counts were obtained by an automated cell counter. Serum iron, total iron binding capacity (TIBC) and ferritin were determined respectively, by colorimetric, turbidimetric methods and chemiluminescence. Blood lead was measured by atomic absorption spectrophotometry. The impact of several parameters for assessment of iron status (haemoglobin, serum iron, TIBC, transferrin saturation, ferritin, red cell indices and red cell distribution width) and variables (gender, age, mother's education, income, body mass index, iron intake, and distance from home to lead-manipulating industry) on blood lead concentration was determined by multiple linear regression. There were significant negative associations between blood lead and the distance from home to the lead-manipulating industry (P < 0.001), Hb (P = 0.019), and ferritin (P=0.023) (R(2)=0.14). Based on these results, further epidemiological studies are necessary to investigate the impact of interventions like iron supplementation or fortification, as an attempt to decrease blood lead in children. (C) 2011 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved. (AU)

Processo FAPESP: 99/09455-1 - O impacto da suplementacao com ferro nos niveis sanguineos de chumbo, em criancas expostas a diferentes niveis de chumbo.
Beneficiário:Patricia Helen de Carvalho Rondó
Modalidade de apoio: Auxílio à Pesquisa - Regular