Silent circulation of plasmid-borne tet(X6) and blaOXA-58 genes in a community-acquired Acinetobacter baumannii strain

Autor(es):Mostrar menos -

Jia, Huiqiong ; Tong, Qingchao ; Wang, Le ; Wu, Yuye ; Li, Xinyang ; Li, Shuangshuang ; Kong, Yingying ; Zhang, Yingying ; Furlan, Pedro Rueda ; Khine, Nwai Oo ; Butaye, Patrick ; Zhang, Jun ; Yang, Qing ; Ruan, Zhi

• Tipo de documento: Artigo Científico
• Fonte: DRUG RESISTANCE UPDATES; v. 79, p. 4-pg., 2024-12-27.

Resumo

To characterize the genomic features of a community-acquired Acinetobacter baumannii strain, co-carrying tet(X6) and blaOXA-58 genes, but was susceptible to tigecycline and carbapenems. The tet(X6) and blaOXA-58 genes were found on a 149,518 bp non-conjugative plasmid. The blaOXA-58 gene was silent, due to the presence of an intact ISAba3-like element upstream, which rendered the strain susceptible to carbapenems. (AU)

• Processo FAPESP: 23/16216-4 - Investigação genômica de probióticos/bacteriocinas para o tratamento de patógenos resistentes a antimicrobianos
• Beneficiário: João Pedro Rueda Furlan
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado