Full-length genomic sequence of hepatitis B virus genotype C2 isolated from a native Brazilian patient

Autor(es)

Alvarado-Mora, Monica Viviana ^[1] ; Ferraz Santana, Rubia Anita ^[2] ; Sitnik, Roberta ^[2] ; Abrao Ferreira, Paulo Roberto ^[3] ; Pitangueira Mangueira, Cristovao Luis ^[2] ; Carrilho, Flair Jose ^[1] ; Rebello Pinho, Joao Renato ^{[2, 1]}

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Med, Inst Trop Med, Lab Gastroenterol & Hepatol Trop, Dept Gastroenter, BR-05403000 Sao Paulo - Brazil

^[2] Hosp Israelita Albert Einstein, Dept Patol Clin, Sao Paulo - Brazil

^[3] Univ Fed Sao Paulo, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Memórias do Instituto Oswaldo Cruz; v. 106, n. 4, p. 495-498, JUN 2011.
• Citações Web of Science: 2

Resumo

The hepatitis B virus (HBV) is among the leading causes of chronic hepatitis, cirrhosis and hepatocellular carcinoma. In Brazil, genotype A is the most frequent, followed by genotypes D and F. Genotypes B and C are found in Brazil exclusively among Asian patients and their descendants. The aim of this study was to sequence the entire HBV genome of a Caucasian patient infected with HBV/C2 and to infer the origin of the virus based on sequencing analysis. The sequence of this Brazilian isolate was grouped with four other sequences described in China. The sequence of this patient is the first complete genome of HBV/C2 reported in Brazil. (AU)

• Processo FAPESP: 08/50461-6 - Estudo da variabilidade genotípica dos vírus da Hepatite B e Hepatite C na Colômbia
• Beneficiário: Monica Viviana Alvarado Mora
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto
• Processo FAPESP: 07/53457-7 - Estudo da variabilidade genotípica dos vírus das Hepatites B e C na Colômbia
• Beneficiário: João Renato Rebello Pinho
• Modalidade de apoio: Auxílio à Pesquisa - Regular