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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Full-length genomic sequence of hepatitis B virus genotype C2 isolated from a native Brazilian patient

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Author(s):
Alvarado-Mora, Monica Viviana [1] ; Ferraz Santana, Rubia Anita [2] ; Sitnik, Roberta [2] ; Abrao Ferreira, Paulo Roberto [3] ; Pitangueira Mangueira, Cristovao Luis [2] ; Carrilho, Flair Jose [1] ; Rebello Pinho, Joao Renato [2, 1]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Fac Med, Inst Trop Med, Lab Gastroenterol & Hepatol Trop, Dept Gastroenter, BR-05403000 Sao Paulo - Brazil
[2] Hosp Israelita Albert Einstein, Dept Patol Clin, Sao Paulo - Brazil
[3] Univ Fed Sao Paulo, Sao Paulo - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Memórias do Instituto Oswaldo Cruz; v. 106, n. 4, p. 495-498, JUN 2011.
Web of Science Citations: 2
Abstract

The hepatitis B virus (HBV) is among the leading causes of chronic hepatitis, cirrhosis and hepatocellular carcinoma. In Brazil, genotype A is the most frequent, followed by genotypes D and F. Genotypes B and C are found in Brazil exclusively among Asian patients and their descendants. The aim of this study was to sequence the entire HBV genome of a Caucasian patient infected with HBV/C2 and to infer the origin of the virus based on sequencing analysis. The sequence of this Brazilian isolate was grouped with four other sequences described in China. The sequence of this patient is the first complete genome of HBV/C2 reported in Brazil. (AU)