| Texto completo | |
| Autor(es): |
Capellaro, Kaue C.
;
Burtoloso, Antonio C. B.
Número total de Autores: 2
|
| Tipo de documento: | Artigo Científico |
| Fonte: | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; v. N/A, p. 6-pg., 2025-08-14. |
| Resumo | |
In this work, a straightforward, rapid, and cost-effective protocol is presented for synthesizing three distinct classes of alpha-functionalized sulfoxonium ylides-alpha-xanthate, alpha-thiocyanate, and alpha-dithiocarbamate-via molecular iodine-mediated reactions. This method demonstrates broad substrate tolerance, including heterocycles and steroids, delivering 25 examples with yields of up to 83%. Experimental studies revealed that iodine reacts with xanthates to form disulfides, which subsequently act as electrophiles for nucleophilic attack by the ylide. (AU) | |
| Processo FAPESP: | 23/02675-7 - Novas metodologias para formação de ligações C-C a partir de ilídeos sulfoxônios |
| Beneficiário: | Antonio Carlos Bender Burtoloso |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |