The Role of Enamel Matrix Derivative Protein in Minimally Invasive Surgery in Treating Intrabony Defects in Single-Rooted Teeth: A Randomized Clinical Trial

Autor(es)

Ribeiro, Fernanda V. ^[1] ; Casarin, Renato C. V. ^[1] ; Junior, Francisco H. N. ^[1] ; Sallum, Enilson A. ^[1] ; Casati, Marcio Z. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Dept Prosthodont & Periodont, Sch Dent Piracicaba, BR-13414903 Piracicaba, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Periodontology; v. 82, n. 4, p. 522-532, APR 2011.
• Citações Web of Science: 21

Resumo

Background: This study investigates the impact of enamel matrix derivative (EMD) proteins on the outcome of a minimally invasive surgical technique (MIST) for the treatment of intrabony defects. Methods: Thirty patients who presented with intrabony defects were randomly assigned to treatment with: 1) MIST plus EMD or 2) MIST alone. Probing depth (PD), position of the gingival margin (PGM), and relative clinical attachment level (RCAL) were evaluated at 3 and 6 months after treatment. Radiographs and markers in gingival crevicular fluid associated with periodontal regeneration were also evaluated. Results: Significant PD reductions, RCAL gains, and no changes in PGM were obtained at 3 and 6 months in both groups. Clinical and radiographic evaluations and levels of mediators of wound healing did not present differences between therapies at any time. Conclusion: The use of EMD did not provide superior benefits on the outcome of the minimally invasive surgical approach for the treatment of intrabony defects. J Periodontol 2011;82:522-532. (AU)

• Processo FAPESP: 08/50027-4 - Avaliação clínica, imunoenzimática e microbiológica na periodontia: do tratamento da doença à regeneração dos defeitos periodontais
• Beneficiário: Márcio Zaffalon Casati
• Modalidade de apoio: Auxílio à Pesquisa - Regular