| Texto completo | |
| Autor(es): |
Santos, Pedro Henrique
;
Marciano, Jessica De Souza
;
da Silva, Daniel J.
;
Camani, Paulo Henrique
;
Ferreira, Greiciele
;
Duran, Adriana Feliciano Alves
;
Camillo, Livia de Moraes Bomediano
;
Bueno, Rodrigo de Freitas
;
Rosa, Derval dos Santos
Número total de Autores: 9
|
| Tipo de documento: | Artigo Científico |
| Fonte: | SOUTH AFRICAN JOURNAL OF BOTANY; v. 189, p. 11-pg., 2026-02-01. |
| Resumo | |
Essential oils (EOs) are complex mixtures of volatile chemical compounds that exhibit diverse bioactive properties, including antimicrobial, antioxidant, anti-inflammatory, and anticancer activities. In this study, the chemical composition and bioactive potential of nine plant-derived EOs were investigated, with particular emphasis on their antiviral activity against SARS-CoV-2 and potential applications in the biomedical field. Gas chromatography-mass spectrometry (GC-MS) was employed to characterize the chemical constituents of the EOs, followed by the evaluation of their antioxidant, antibacterial, and antiviral activities. Among the tested oils, clove leaf EO (Eugenia caryophyllata) exhibited the most notable performance, with an EC50 value of 20.40 mu g/mL, as well as low minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values against human pathogenic bacteria. These biological effects are attributed to the high content of the phenolic compound eugenol (88.76 %) present in clove EO. Furthermore, all EOs demonstrated promising antiviral effects against SARS-CoV-2, as determined by RT-qPCR, with rosemary EO showing the greatest reduction in viral replication after 30 min of exposure. The synergistic action of 1,8-cineole and alpha-pinene in rosemary EO likely contributed to this enhanced antiviral activity. Overall, the findings indicate that, depending on their chemical composition, essential oils possess significant antibacterial and antiviral potential, highlighting their promise as bioactive agents for future biomedical applications. (AU) | |
| Processo FAPESP: | 20/13703-3 - Materiais porosos ecológicos para a recuperação e reavaliação de metais recuperados de água contaminada |
| Beneficiário: | Derval dos Santos Rosa |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 23/11229-0 - Membranas porosas biodegradáveis de celulose in natura e funcionalizadas com diferentes agentes modificadores para remoção e recuperação de EPTs de águas contaminadas |
| Beneficiário: | Paulo Henrique Camani |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |
| Processo FAPESP: | 24/15696-5 - Membranas nanocompósitas contendo nanopartículas quimicamente modificadas com plasma: o efeito do plasma para desenvolver membranas de alta performance para remediação ambiental |
| Beneficiário: | Paulo Henrique Camani |
| Modalidade de apoio: | Bolsas no Exterior - Estágio de Pesquisa - Pós-Doutorado |