Working memory impairment in multiple sclerosis relapsing-remitting patients with episodic memory deficits

Autor(es)

Fuso, Simone Freitas ^[1] ; Callegaro, Dagoberto ^[2] ; Pompeia, Sabine ^[1] ; Bueno, Orlando F. A. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Ctr Myelin Disorders, Clin Hosp, Dept Neurol, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Arquivos de Neuro-Psiquiatria; v. 68, n. 2, p. 205-211, APR 2010.
• Citações Web of Science: 8

Resumo

Episodic memory is impaired in multiple sclerosis (MS) patients, possibly because of deficits in working memory (WM) functioning. If so, WM alterations should necessarily be found in patients with episodic memory deficits, but this has not yet been demonstrated. In this study we aimed at determining whether episodic memory deficits in relapsing-remitting MS are found in conjunction with impaired WM. We evaluated 32 MS patients and 32 matched healthy controls. Nineteen of the 32 patients had episodic memory impairment, and as a group only these individuals showed deficits in WM capacity, which may lead to difficulty in encoding, and/or retrieving information from episodic memory. (AU)

• Processo FAPESP: 01/06699-9 - Processamento de informação em pacientes portadores de esclerose múltipla: tentativa de compreensão dos déficits de memória
• Beneficiário: Simone Freitas Fuso
• Modalidade de apoio: Bolsas no Brasil - Mestrado