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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Working memory impairment in multiple sclerosis relapsing-remitting patients with episodic memory deficits

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Author(s):
Fuso, Simone Freitas [1] ; Callegaro, Dagoberto [2] ; Pompeia, Sabine [1] ; Bueno, Orlando F. A. [1]
Total Authors: 4
Affiliation:
[1] Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo - Brazil
[2] Univ Sao Paulo, Ctr Myelin Disorders, Clin Hosp, Dept Neurol, Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Arquivos de Neuro-Psiquiatria; v. 68, n. 2, p. 205-211, APR 2010.
Web of Science Citations: 8
Abstract

Episodic memory is impaired in multiple sclerosis (MS) patients, possibly because of deficits in working memory (WM) functioning. If so, WM alterations should necessarily be found in patients with episodic memory deficits, but this has not yet been demonstrated. In this study we aimed at determining whether episodic memory deficits in relapsing-remitting MS are found in conjunction with impaired WM. We evaluated 32 MS patients and 32 matched healthy controls. Nineteen of the 32 patients had episodic memory impairment, and as a group only these individuals showed deficits in WM capacity, which may lead to difficulty in encoding, and/or retrieving information from episodic memory. (AU)