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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Isolation of Candida dubliniensis from denture wearers

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Autor(es):
Gasparoto, Thais Helena [1] ; Dionisio, Thiago Jose [1] ; de Oliveira, Carine Ervolino [2] ; Porto, Vinicius Carvalho [3] ; Gelani, Valeria [1] ; Santos, Carlos Ferreira [1] ; Campanelli, Ana Paula [1] ; Lara, Vanessa Soares [2]
Número total de Autores: 8
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Bauru Sch Dent, Dept Biol Sci, Bauru, SP - Brazil
[2] Univ Sao Paulo, Bauru Sch Dent, Dept Stomatol Pathol, Bauru, SP - Brazil
[3] Univ Sao Paulo, Bauru Sch Dent, Dept Prosthodont, Bauru, SP - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: Journal of Medical Microbiology; v. 58, n. 7, p. 959-962, JUL 2009.
Citações Web of Science: 23
Resumo

Candida albicans is considered the most important Candida species able to cause oral infections in denture wearers. In recent years, Candida dubliniensis has emerged as a pathogenic yeast in humans. The close phenotypic similarities of C. albicans and C. dubliniensis have led to the misidentification of these species. In this work, our aim was to verify through PCR the presence of C. dubliniensis in palate and maxillary denture samples from 112 denture wearers presenting with or without denture-related stomatitis (DRS). C. dubliniensis was isolated at low rates from both palate (5.3% and 10.7%) and maxillary denture (5.3% and 8.9%) samples from wearers regardless of the presence of the disease. However, when C. dubliniensis was detected in individuals with DRS, it was always associated with C. albicans. In addition, our results showed that C. albicans was the most commonly identified candidal species in maxillary denture and hard palate samples from DRS patients (78.5% and 89.2%, respectively) as well as from controls (31.2% and 28.5%, respectively). In conclusion, C. dubliniensis was detected in the oral environment of denture wearers. The association of C. dubliniensis with C. albicans occurred in approximately 10% of the DRS cases. (AU)

Processo FAPESP: 05/60668-9 - Estudo da função dos neutrófilos nos mecanismos de defesa contra a estomatite por dentadura em indivíduos idosos
Beneficiário:Thaís Helena Gasparoto
Modalidade de apoio: Bolsas no Brasil - Doutorado
Processo FAPESP: 06/59612-1 - Senescencia e estomatite por dentadura: avaliacao quantitativa, funcional e fenotipica dos neutrofilos.
Beneficiário:Vanessa Soares Lara
Modalidade de apoio: Auxílio à Pesquisa - Regular