| Full text | |
| Author(s): |
Gasparoto, Thais Helena
[1]
;
Dionisio, Thiago Jose
[1]
;
de Oliveira, Carine Ervolino
[2]
;
Porto, Vinicius Carvalho
[3]
;
Gelani, Valeria
[1]
;
Santos, Carlos Ferreira
[1]
;
Campanelli, Ana Paula
[1]
;
Lara, Vanessa Soares
[2]
Total Authors: 8
|
| Affiliation: | [1] Univ Sao Paulo, Bauru Sch Dent, Dept Biol Sci, Bauru, SP - Brazil
[2] Univ Sao Paulo, Bauru Sch Dent, Dept Stomatol Pathol, Bauru, SP - Brazil
[3] Univ Sao Paulo, Bauru Sch Dent, Dept Prosthodont, Bauru, SP - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | Journal of Medical Microbiology; v. 58, n. 7, p. 959-962, JUL 2009. |
| Web of Science Citations: | 23 |
| Abstract | |
Candida albicans is considered the most important Candida species able to cause oral infections in denture wearers. In recent years, Candida dubliniensis has emerged as a pathogenic yeast in humans. The close phenotypic similarities of C. albicans and C. dubliniensis have led to the misidentification of these species. In this work, our aim was to verify through PCR the presence of C. dubliniensis in palate and maxillary denture samples from 112 denture wearers presenting with or without denture-related stomatitis (DRS). C. dubliniensis was isolated at low rates from both palate (5.3% and 10.7%) and maxillary denture (5.3% and 8.9%) samples from wearers regardless of the presence of the disease. However, when C. dubliniensis was detected in individuals with DRS, it was always associated with C. albicans. In addition, our results showed that C. albicans was the most commonly identified candidal species in maxillary denture and hard palate samples from DRS patients (78.5% and 89.2%, respectively) as well as from controls (31.2% and 28.5%, respectively). In conclusion, C. dubliniensis was detected in the oral environment of denture wearers. The association of C. dubliniensis with C. albicans occurred in approximately 10% of the DRS cases. (AU) | |
| FAPESP's process: | 05/60668-9 - Study of neutrophils from elderly in the defense mechanisms against Candida-related denture stomatitis |
| Grantee: | Thaís Helena Gasparoto |
| Support Opportunities: | Scholarships in Brazil - Doctorate |