Dyskeratosis Congenita - Report of a Case with Emphasis on Gingival Aspects

Autor(es)

Lourenco, Silvia V. ^[1] ; Boggio, Paula A. ^[2] ; Fezzi, Fernando A. ^[2] ; Sebastiao, Alexandre L. ^[2] ; Nico, Marcello Menta S. ^[2]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Odontol, Disciplina Patol Geral, Dept Gen Pathol, BR-05508000 Sao Paulo - Brazil

^[2] Univ Sao Paulo, Sch Med, Dept Dermatol, Hosp Clin, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: PEDIATRIC DERMATOLOGY; v. 26, n. 2, p. 176-179, MAR-APR 2009.
• Citações Web of Science: 4

Resumo

A case of dyskeratosis congenita (DC) of an 11-year-old male is reported. He presented with the characteristic clinical triad of reticular pigmentation of the skin, dystrophic nails and oral lesions, and up to the present he had not developed hematological compromise. Oral lesions consisted of extensive tongue erosions and keratosis, and exuberant gingivitis associated. Appropriate periodontal treatment was performed with discrete improvement only. We emphasize that severe gingival inflammation, although infrequent, may represent an alteration specific to DC and therefore should be considered as an additional sign of this syndrome. (AU)

• Processo FAPESP: 02/02676-7 - Expressão genética da integrina beta 1 no desenvolvimento das glândulas salivares humanas: análise da relação com proliferação e diferenciação glandular
• Beneficiário: Silvia Vanessa Lourenço
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores