The predicted subcellular localisation of the sugarcane proteome

Autor(es)

Vicentini, Renato ^[1] ; Menossi, Marcelo ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, UNICAMP, Inst Biol, Dept Genet & Evolucao, Lab Genoma Func, BR-13083970 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: FUNCTIONAL PLANT BIOLOGY; v. 36, n. 3, p. 242-250, 2009.
• Citações Web of Science: 4

Resumo

Plant cells are highly organised, and many biological processes are associated with specialised subcellular structures. Subcellular localisation is a key feature of proteins, since it is related to biological function. The subcellular localisation of such proteins can be predicted, providing information that is particularly relevant to those proteins with unknown or putative function. We performed the first in silico genome-wide subcellular localisation analysis for the sugarcane transcriptome (with 11 882 predicted proteins) and found that most of the proteins were localised in four compartments: nucleus (44%), cytosol (19%), mitochondria (12%) and secretory destinations (11%). We also showed that similar to 19% of the proteins were localised in multiple compartments. Other results allowed identification of a potential set of sugarcane proteins that could show dual targeting by the use of N-truncated forms that started from the nearest downstream in-frame AUG codons. This study was a first step in increasing knowledge about the subcellular localisation of the sugarcane proteome. (AU)

• Processo FAPESP: 05/58104-0 - Localizacao subcelular de proteinas de cana-de-acucar (saccharum spp.): caracterizacao in silico e avaliacao funcional em larga escala.
• Beneficiário: Marcelo Menossi Teixeira
• Modalidade de apoio: Auxílio à Pesquisa - Regular