Estimate of Dementia Prevalence in a Community Sample from Sao Paulo, Brazil

Autor(es)

Bottino, Cassio M. C. ^{[1, 2]} ; Azevedo, Jr., Dionisio ^{[1, 2]} ; Tatsch, Mariana ^{[1, 2]} ; Hototian, Sergio R. ^{[1, 2]} ; Moscoso, Marco A. ^{[1, 2]} ; Folquitto, Jefferson ^{[1, 2]} ; Scalco, Andreia Z. ^{[1, 2]} ; Bazzarella, Mario C. ^{[1, 2]} ; Lopes, Marcos A. ^{[1, 2]} ; Litvoc, Julio ^[3]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Med, Dept Psychiat, BR-05508 Sao Paulo - Brazil

^[2] Inst Psiquiatria HC FM USP, Old Age Res Grp PROTER, BR-05403010 Sao Paulo - Brazil

^[3] Univ Sao Paulo, Fac Med, Dept Prevent Med, BR-05508 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS; v. 26, n. 4, p. 291-299, 2008.
• Citações Web of Science: 65

Resumo

Aims: To estimate dementia prevalence and describe the etiology of dementia in a community sample from the city of Sao Paulo, Brazil. Methods: A sample of subjects older than 60 years was screened for dementia in the first phase. During the second phase, the diagnostic workup included a structured interview, physical and neurological examination, laboratory exams, a brain scan, and DSM-IV criteria diagnosis. Results: Mean age was 71.5 years (n = 1,563) and 58.3% had up to 4 years of schooling (68.7% female). Dementia was diagnosed in 107 subjects with an observed prevalence of 6.8%. The estimate of dementia prevalence was 12.9%, considering design effect, nonresponse during the community phase, and positive and negative predictive values. Alzheimer's disease was the most frequent cause of dementia (59.8%), followed by vascular dementia (15.9%). Older age and illiteracy were significantly associated with dementia. Conclusions: The estimate of dementia prevalence was higher than previously reported in Brazil, with Alzheimer's disease and vascular dementia being the most frequent causes of dementia. Dementia prevalence in Brazil and in other Latin American countries should be addressed by additional studies to confirm these higher dementia rates which might have a sizable impact on countries' health services. Copyright (C) 2008 S. Karger AG, Basel (AU)

• Processo FAPESP: 01/05959-7 - Demência e transtornos cognitivos em idosos: um estudo clínico-epidemiológico em dois municípios do estado de São Paulo
• Beneficiário: Cássio Machado de Campos Bottino
• Modalidade de apoio: Auxílio à Pesquisa - Regular