Clinical, Histological, and Microbiological Findings in Peri-Implant Disease: A Pilot Study

Autor(es)

Ferreira, Jr., Samuel Barros ^[1] ; Figueiredo, Caio Marcio ^[2] ; Pompeia Fraga Almeida, Ana Lucia ^[1] ; Assis, Gerson Francisco ^[3] ; Dionisio, Thiago Jose ; Santos, Carlos Ferreira ^[4]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Hosp Rehabil Craniofacial Anomalies, Sect Periodontol, Bauru - Brazil

^[2] Univ Sao Paulo, Hosp Rehabil Craniofacial Anomalies, Sect Implantodontol, Bauru - Brazil

^[3] Univ Sao Paulo, Bauru Sch Dent, Dept Biol Sci, Discipline Histol, Bauru - Brazil

^[4] Univ Sao Paulo, Bauru Sch Dent, Discipline Pharmacol, Dept Biol Sci, Bauru - Brazil

• Tipo de documento: Artigo Científico
• Fonte: IMPLANT DENTISTRY; v. 18, n. 4, p. 334-344, AUG 2009.
• Citações Web of Science: 10

Resumo

Objectives: This study is intended to verify the correlation among clinical indices of the peri-implant soft tissues, the histological condition and the presence of 3 pathogens commonly associated with peri-implant diseases (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, and Tannerella forsythia). Materials: Four clinical indices, Gingival Index (GI), Sulcus Bleeding Index, GI modified by Mombelli, and Plaque Index modified by Mombelli (mPI) were evaluated around I dental implant of each subject (n = 10). Subgingival plaque was collected for bacterial analysis (polymerase chain reaction) and a biopsy of peri-implant soft tissues for histological analysis was harvested. The clinical indices and detected pathogens correlated with a developed histological index (HI). Results: There was no statistically significant relationship between the clinical indices (GI, Sulcus Bleeding Index, and GI modified by Mombelli) and the HI, except for the mPI on the central area of lingual aspects (r = 0.85, P = 0.0029). There was a tendency for a positive correlation between the mPI on the central area of buccal aspects and the HI (r = 0.63, P = 0.0544). The counting of lymphocytes and plasmocytes correlated positively with 111, thus suggesting the index reliability. The prevalence of A. actinomycetemcomitans, P. gingivalis, and T. forsythia did not present a significant relationship with the HI. Conclusion: Despite the small number of samples and the poor statistical significance, the mPI seems to be useful for evaluation of inflammatory severity on soft tissue around dental implants as demonstrated by its relationship with the HI. Further studies are necessary to elucidate this subject. (Implant Dent 2009;18:334-344) (AU)

• Processo FAPESP: 02/09380-6 - Metabolitos do acido araquidonico e suas vias enzimaticas na doenca periodontal humana.
• Beneficiário: Carlos Ferreira dos Santos
• Modalidade de apoio: Auxílio à Pesquisa - Regular