Molecular Adaptations to Concurrent Training

Autor(es):Mostrar menos -

de Souza, E. O. ^[1] ; Tricoli, V. ^[1] ; Roschel, H. ^[1] ; Brum, P. C. ^[1] ; Bacurau, A. V. N. ^[1] ; Ferreira, J. C. B. ^{[1, 2]} ; Aoki, M. S. ^[3] ; Neves-, Jr., M. ^[4] ; Aihara, A. Y. ^[5] ; Correa Fernandes, A. da Rocha ^[6] ; Ugrinowitsch, C. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Phys Educ & Sport, Dept Sport, BR-05508030 Sao Paulo - Brazil

^[2] Stanford Univ, Sch Med, Stanford, CA 94305 - USA

^[3] Univ Sao Paulo, Sch Arts, Sao Paulo - Brazil

^[4] Univ Sao Paulo, Sch Med, Sao Paulo - Brazil

^[5] DASA, , Sao Paulo - Brazil

^[6] Univ Fed Sao Paulo, Dept Radiol, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF SPORTS MEDICINE; v. 34, n. 3, p. 207-213, MAR 2013.
• Citações Web of Science: 22

Resumo

This study investigated the chronic effects of concurrent training (CT) on morphological and molecular adaptations. 37 men (age = 23.7 +/- 5.5 year) were divided into 4 groups: interval (IT), strength (ST) and concurrent (CT) training and a control group (C) and underwent 8 weeks of training. Maximum strength (1RM) and muscle cross-sectional area (CSA) were evaluated before and after training. Muscle samples were obtained before the training program and 48 h after the last training session. VO2max improved in 5 +/- 0.95 % and 15 +/- 1.3 % (pre- to post-test) in groups CT and IT, respectively, when compared to C. Time to exhaustion (TE) improved from pre- to post-test when compared to C (CT = 6.1 +/- 0.58 %; IT = 8.3 +/- 0.88 %; ST = 3.2 +/- 0.66 %). 1RM increased from pre-to post-test only in ST and CT groups (ST = 18.5 +/- 3.16 %; CT = 17.6 +/- 3.01 %). Similarly, ST and CT groups increased quadriceps CSA from pre-to post-test (6.2 +/- 1.4 %; 7.8 +/- 1.66 %). The p70S6K1 total protein content increased after CT. The ST group showed increased Akt phosphorylation at Ser473 (45.0 +/- 3.3 %) whereas AMPK phosphorylation at Thr172 increased only in IT group, (100 +/- 17.6 %). In summary, our data suggest that despite the differences in molecular adaptations between training regimens, CT did not blunt muscle strength and hypertrophy increments when compared with ST. (AU)

• Processo FAPESP: 09/03143-1 - Controle de qualidade de proteína na insuficiência cardíaca: papel das diferentes isoformas de proteína quinase C
• Beneficiário: Julio Cesar Batista Ferreira
• Linha de fomento: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 07/02738-6 - Efeito do treinamento concorrente na expressão gênica associada à hipertrofia muscular
• Beneficiário: Eduardo Oliveira de Souza
• Linha de fomento: Bolsas no Brasil - Mestrado
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• Beneficiário: Hamilton Augusto Roschel da Silva
• Linha de fomento: Bolsas no Brasil - Pós-Doutorado