Association between Maximal Aerobic Capacity and Psychosocial Factors in Adults With Moderate-to-Severe Asthma

Autor(es)

Mendes, Felipe A. R. ^[1] ; Lunardi, Adriana C. ^[1] ; Silva, Ronaldo A. ^[1] ; Cukier, Alberto ^[2] ; Stelmach, Rafael ^[2] ; Martins, Milton A. ^[3] ; Carvalho, Celso R. F. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Dept Phys Therapy, Sch Med, BR-01246903 Sao Paulo - Brazil

^[2] Univ Sao Paulo, Dept Pulm Dis, Sch Med, BR-01246903 Sao Paulo - Brazil

^[3] Univ Sao Paulo, Dept Med, Sch Med, BR-01246903 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF ASTHMA; v. 50, n. 6, p. 595-599, AUG 2013.
• Citações Web of Science: 6

Resumo

Background. The symptoms of asthma impair health-related quality of life (HRQoL), increase anxiety and depression and may keep subjects from engaging in physical exercise. Physical inactivity has been related to poor asthma outcomes; however, the association between physical fitness and psychosocial disorders remains poorly understood. Objective. To verify the association between aerobic capacity, HRQoL, and psychological distress in adults with moderate or severe persistent asthma who were clinically stable. Methods. Eighty-eight participants (68 females) with either moderate or severe persistent asthma (age range, 20-60 years) who were under medical treatment for at least 6 months and considered clinically stable were studied. Participants were evaluated on two non-consecutive days. On the first day, the HRQoL, depression and anxiety levels and pulmonary function were assessed. On the second day, subjects underwent cardiopulmonary exercise testing. Results. Using the agglomerative cluster approach, two clusters were identified: 21 participants (24%) were grouped in Cluster 1, and 67 (76%) were grouped in Cluster 2. Asthmatic subjects from Cluster 1 exhibited increased aerobic capacity, better HRQoL and lower depression levels than did subjects in Cluster 2 (p<.05). No difference was observed between the clusters with respect to gender, age, body mass index (BMI) or pulmonary function (p>.05). The discriminant function model exhibits good accuracy (R-2 = 0.79) and predicted 93% of the case allocations. Conclusion. Our results suggest an association between reduced exercise capacity, low HRQoL and increases in depressive symptoms in clinically stable asthmatic subjects. These results suggest the need to assess physical fitness and psychosocial distress during asthma treatment and the importance of a multidisciplinary approach. (AU)

• Processo FAPESP: 07/56937-0 - Efeito do treinamento fisico na resposta autonomica e sua correlacao com a inflamacao pulmonar em pacientes com asma persistente moderada ou grave.
• Beneficiário: Felipe Augusto rodrigues Mendes
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 02/08422-7 - Mecanismos de inflamação pulmonar na asma: estudos clínicos e experimentais
• Beneficiário: Milton de Arruda Martins
• Modalidade de apoio: Auxílio à Pesquisa - Temático