Liquid chromatography/electrospray ionization tandem mass spectrometry profiling of compounds from the infusion of Byrsonima fagifolia Niedenzu

Autor(es)

Sannomiya, Miriam ; Santos, Lourdes Campaner dos ; Carbone, Virginia ; Napolitano, Assunta ; Piacente, Sonia ; Pizza, Cosimo ; Souza-Brito, Alba R. M. ; Vilegas, Wagner ^[8]

• Tipo de documento: Artigo Científico
• Fonte: Rapid Communications in Mass Spectrometry; v. 21, p. 1393-1400, 2007.
• Área do conhecimento: Ciências Exatas e da Terra - Química
• Assunto(s): Espectrometria de massas em Tandem Cromatografia líquida de alta pressão Espectrometria de massas por ionização por electrospray Malpighiaceae

Resumo

A rapid analytical approach suitable to achieve a comprehensive characterization of the compounds present in the infusion prepared from the leaves of Byrsonima fagifolia Niedenzu (Malpighiaceae), a Brazilian plant used as an infusion to treat gastric disorders, was developed. The method was based on high-performance liquid chromatography coupled to electrospray negative ionisation multistage ion trap mass spectrometry (HPLC/ESI-ITMSn).The main ions in the ESI-ITMS spectra were attributed to a quinic acid core containing from one to five galloyl units. Quercetin derivatives containing one and two sugar moieties as well as galloyl esterification were also detected. These results indicated that HPLC/ESI-ITMSn is easily applicable to infusions of this plant and allows the rapid and direct identification of these compounds in crude plant extracts. (AU)

• Processo FAPESP: 02/05503-6 - Uso sustentável da biodiversidade brasileira: prospecção químico-farmacológica em plantas superiores
• Beneficiário: Wagner Vilegas
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Temático