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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Tobacco Smoke Exposure during Childhood: Effect on Cochlear Physiology

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Autor(es):
Durante, Alessandra S. [1] ; Pucci, Beatriz [2] ; Gudayol, Nicolly [2] ; Massa, Beatriz [1] ; Gameiro, Marcella [1] ; Lopes, Cristiane [1]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Arnaldo Vieira de Carvalho Fdn, FCMSCSP, Sch Med Sci Santa Casa Sao Paulo, BR-01221020 Sao Paulo - Brazil
[2] Santa Casa Sisters Mercy Hosp Sao Paulo, ISCMSP, BR-01221020 Sao Paulo - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH; v. 10, n. 11, p. 5257-5265, NOV 2013.
Citações Web of Science: 11
Resumo

The rate of smoking in Brazil is about 18.8%. Exposure to environmental tobacco smoke is one of the major factors predisposing children to several hazardous health problems. The objective of the present research was to analyze the effect of tobacco smoke exposure during childhood on cochlear physiology by measuring the transient evoked otoacoustic emissions (TEOAE) response levels. Cotinine, the main metabolite of nicotine, was measured in 145 students' (8-10 years old) urine. Sixty students indicated tobacco smoke exposure (TSE) (cotinine urine levels >= 5.0 ng/mL) and 85 did not. The evaluation of TEOAE of TSE students showed lower response levels, mainly on frequencies of 2.8 kHz on the right and left ears and 2.0 kHz on left ear and lower signal noise response levels, mainly on the 1.0 kHz and 1.4 kHz frequencies, when compared to controls that were not exposed to tobacco. The mean reduction observed in TEOAE of tobacco smoke exposure children was 2.1 dB SPL. These results have important implications on the damage to the cochlear structures and indicate a possible loss in hearing and hearing ability development. (AU)

Processo FAPESP: 12/00870-2 - Efeito do fumo passivo nas medidas de audição de escolares
Beneficiário:Alessandra Spada Durante
Modalidade de apoio: Auxílio à Pesquisa - Regular