Prevalence of antibodies to spotted fever group rickettsiae in humans and domestic animals in a Brazilian spotted fever-endemic area in the State of São Paulo, Brazil: serologic evidence for infection by Rickettsia rickettsii and another spotted fever group rickettsia

Autor(es)

Labruna, M. B. ; Sangioni, L. A. ; Vianna, M. C. B. ; Gennari, S. M. ; Galvão, M. A. M. ; Mafra, C. L. ; Vidotto, O. ; Schumaker, T. S. T. ; Walker, D. H. ; Horta, M. C. ^[10]

• Tipo de documento: Artigo Científico
• Fonte: American Journal of Tropical Medicine and Hygiene; v. 71, n. 1, p. 93-97, Jul. 2004.
• Área do conhecimento: Ciências Agrárias - Medicina Veterinária
• Assunto(s): Rickettsioses em animais Febre maculosa

Resumo

In serum samples obtained from all the healthy humans, horses, dogs, and donkeys present on three farms in the Pedreira Municipality, an endemic area for Brazilian spotted fever, an indirect immunofluorescence assay (IFA) detected antibodies against Rickettsia rickettsii in 17 (77.3%) horses, 5 (31.3%) dogs (titers ranging from 64 to 4,048), and none of 4 donkeys or 50 humans. Five canine and eight equine sera with high antibody titers to R. rickettsii were also tested by IFA against R. bellii, R. akari, and R. africae antigens. Sera from two horses and two dogs that showed similar high antibody titers against two rickettsial antigens were evaluated after cross-absorption. Sera from seven horses and two dogs contained antibodies specific for R. rickettsii, and one dog serum had antibodies against a Rickettsia species very closely related to R. africae. The latter may have been caused by infection with the recently identified COOPERI strain. (AU)

• Processo FAPESP: 00/02711-1 - Aspectos epidemiológicos da febre maculosa nos Estados de Minas Gerais e São Paulo
• Beneficiário: Solange Maria Gennari
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 02/00644-0 - Estudo de riquetsioses e arboviroses transmitidos por carrapatos de diferentes áreas do Brasil
• Beneficiário: Marcelo Bahia Labruna
• Modalidade de apoio: Bolsas no Exterior - Pesquisa