| Texto completo | |
| Autor(es): Mostrar menos - |
Nagata, Maria J. H.
[1]
;
de Campos, Natalia
[1]
;
Messora, Michel R.
[2]
;
Pola, Natalia M.
[1]
;
Santinoni, Carolina S.
[1]
;
Bomfim, Suely R. M.
[3]
;
Fucini, Stephen E.
[1]
;
Ervolino, Edilson
[4]
;
de Almeida, Juliano M.
[1]
;
Theodoro, Leticia H.
[1]
;
Garcia, Valdir G.
[1]
Número total de Autores: 11
|
| Afiliação do(s) autor(es): | [1] Sao Paulo State Univ, UNESP, Dent Sch Aracatuba, Dept Surg & Integrated Clin, Aracatuba, SP - Brazil
[2] Univ Sao Paulo, Ribeirao Preto Sch Dent, Dept Oral & Maxillofacial Surg & Traumatol, USP, Ribeirao Preto, SP - Brazil
[3] Sao Paulo State Univ, Vet Sch Aracatuba, Dept Clin Surg & Anim Reprod, Sao Paulo - Brazil
[4] Sao Paulo State Univ, UNESP, Dept Basic Sci, Dent Sch Aracatuba, Sao Paulo - Brazil
Número total de Afiliações: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Journal of Periodontology; v. 85, n. 6, p. 770-778, JUN 2014. |
| Citações Web of Science: | 8 |
| Resumo | |
Background: This study histomorphometrically analyzes the influence of platelet- rich plasma (PRP), low- level laser therapy (LLLT), or their combination on the healing of periodontal fenestration defects (PFDs) in rats. Methods: PFDs were surgically created in the mandibles of 80 rats. The animals were randomly divided into four groups: 1) C (control) and 2) PRP, defects were filled with blood clot or PRP, respectively; 3) LLLT and 4) PRP/LLLT, defects received laser irradiation, were filled with blood clot or PRP, respectively, and then irradiated again. Animals were euthanized at either 10 or 30 days post-surgery. Percentage of new bone (NB), density of newly formed bone (DNB), new cementum (NC), and extension of remaining defect (ERD) were histomorphometrically evaluated. Data were statistically analyzed (analysis of variance; Tukey test, P < 0.05). Results: At 10 days, group PRP presented ERD significantly lower than group C. At 30 days, group PRP presented NB and DNB significantly greater than group C. Groups LLLT, PRP, and PRP/LLLT showed significant NC formation at 30 days, with collagen fibers inserted obliquely or perpendicularly to the root surface. NC formation was not observed in any group C specimen. Conclusions: LLLT, PRP, or their combination all promoted NC formation with a functional periodontal ligament. The combination PRP/LLLT did not show additional positive effects compared to the use of either therapy alone. (AU) | |
| Processo FAPESP: | 08/52608-4 - Avaliacao da influencia do plasma rico em plaquetas e do laser de baixa intensidade na cicatrizacao de defeitos de fenestracao periodontal em ratos. estudo histologico e histometrico. |
| Beneficiário: | Natália de Campos Kajimoto |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |