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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Creativity and executive function across manic, mixed and depressive episodes in bipolar I disorder

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Autor(es):
Soeiro-de-Souza, Marcio Gerhardt [1] ; Dias, Vasco Videira [2] ; Bio, Danielle Soares [3] ; Post, Robert M. [4] ; Moreno, Ricardo A. [5]
Número total de Autores: 5
Afiliação do(s) autor(es):
[1] Univ Sao Paulo. Sch Med
[2] Univ Lisbon. Fac Med
[3] Univ Sao Paulo. Sch Med
[4] Bipolar Collaborat Network. Bethesda
[5] Univ Sao Paulo. Sch Med
Número total de Afiliações: 5
Tipo de documento: Artigo Científico
Fonte: Journal of Affective Disorders; v. 135, n. 1-3, p. 292-297, DEC 2011.
Citações Web of Science: 13
Resumo

Introduction: Creativity is a complex construct involving affective and cognitive components. Bipolar Disorder (BD) has been associated with creativity and is characterized by a wide range of affective and cognitive symptoms. Although studies of creativity in BD have tended to focus on creativity as a trait variable in medicated euthymic patients, it probably fluctuates during symptomatic states of BD. Since creativity is known to involve key affective and cognitive components, it is plausible to speculate that cognitive deficits and symptoms present in symptomatic BD could interfere with creativity. Material and methods: Sixty-seven BD type I patients medication free, age 18-35 years and experiencing a maniac, mixed, or depressive episodes, were assessed for creativity, executive functioning, and intelligence. Results: Manic and mixed state patients had higher creativity scores than depressive individuals. Creativity was influenced by executive function measures only in manic patients. Intelligence did not influence creativity for any of the mood episode types. Conclusion: We propose that creativity in BD might be linked to the putative hyperdopaminergic state of mania and be dependent on intact executive function. Future studies should further explore the role of dopaminergic mechanisms in creativity in BD. (C) 2011 Elsevier B.V. All rights reserved. (AU)

Processo FAPESP: 10/06230-0 - Estudo genético de associação entre polimorfismos de nucleotídeo único e desempenho cognitivo em pacientes bipolares tipo I jovens: Licavalgene
Beneficiário:Ricardo Alberto Moreno
Modalidade de apoio: Auxílio à Pesquisa - Regular