I Workshop de Neuroplasticidade - Neuroplasticidade de suas implicações na neuropsicofarmacologia

• Processo: 18/02170-4
• Modalidade de apoio: Auxílio Organização - Reunião Científica
• Data de Início da vigência: 04 de junho de 2018
• Data de Término da vigência: 06 de junho de 2018
• Área do conhecimento: Ciências Biológicas - Farmacologia - Neuropsicofarmacologia
• Pesquisador responsável: Alline Cristina de Campos
• Beneficiário: Alline Cristina de Campos
• Instituição Sede: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brasil
• Assunto(s): Psicofarmacologia Fatores de crescimento neural Plasticidade neuronal Psicotrópicos
• Palavra(s)-Chave do Pesquisador: neurogênese adulta | Neuroplasticidade | Neurotrofinas | Psicofarmacos | transtornos neuropsiquiátricos | Psicofarmacologia

Resumo

In neuroscience, the term neuroplasticity applies to the capacity of the brain to adapt and change in response to experience (Fuchs and Flugue, 2014). William James was the first to propose this term in 1890, defending the idea that brain functions are not fixed during life (James, 1890). Notably, the concept of neuroplasticity has expanded to include not only changes at a morphological level but also biochemical and pharmacological adaptations (intracellular pathways, receptors, synaptic proteins), alterations in neuronal networks (changes in connectivity, dendritic remodeling, and number and morphology of dendritic spines), as well as the generation of new neurons (i.e., adult neurogenesis) (Fuchs and Flugue, 2014). These neuroplastic modifications, moreover, can be either adaptive or maladaptive. Therefore, the mechanisms responsible for these changes may be a great window of opportunity for understanding the pathophysiology and treatment of mental illness (Kays et al., 2012).The aim of the workshop is to discuss with the attendants the most important aspects of the current knowledge involving the theme Neuroplasticity and its interface with pharmacology. During the workshop, attendants will have the opportunity of being contact and discuss with researchers several aspects related to neuroplasticity. Additionally, they will have the chance to present their results as poster or oral presentations. Brazilian researchers and international guests with expertise in the subject will sponsor all activities proposed here. Everything will be planned to facilitate the exchange of knowledge, encouraging live discussions and future collaborations. In addition to academic activities, extracurricular activities will be stimulated during meals and social events during the free time. (AU)