Human flicker electroretinography using different temporal modulations at mesopic and photopic luminance levels

Autor(es)

Nagy, Balazs Vince ^{[1, 2, 3]} ; Salgueiro Barboni, Mirella Telles ^{[1, 2]} ; Gomes Martins, Cristiane Maria ^{[1, 2]} ; da Costa, Marcelo Fernandes ^{[1, 2]} ; Kremers, Jan ^[4] ; Ventura, Dora Fix ^{[1, 2]}

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Psychol, Dept Expt Psychol, BR-05508030 Sao Paulo - Brazil

^[2] Univ Sao Paulo, BR-05508030 Sao Paulo - Brazil

^[3] Budapest Univ Technol & Econ, Dept Mech Opt & Engn Informat, Budapest - Hungary

^[4] Univ Hosp Erlangen, Dept Ophthalmol, Erlangen - Germany

• Tipo de documento: Artigo Científico
• Fonte: DOCUMENTA OPHTHALMOLOGICA; v. 129, n. 2, p. 129-138, OCT 2014.
• Citações Web of Science: 3

Resumo

Electroretinographic measurement instruments allow the variation of several stimulation parameters enabling to study a wide range of retinal processes. The purpose of the present study was to measure human flicker electroretinograms (ERGs) varying temporal modulation, temporal frequency and mean luminance in the photopic and higher mesopic ranges where the change from cone to rod dominance occurs. Fourteen healthy subjects (mean age = 31 +/- A 6) participated in this study. ERG recordings were performed with the RetiPort system (Roland Consult, Germany). The stimuli were ON and OFF sawtooth waves, square wave and sine wave. The temporal frequencies were 4 and 8 Hz. The mean luminance varied from 1 to 60 cd/m(2). The results confirmed the possibility to distinguish between rod- and cone-dominated retinal responses when using the flicker ERG at different temporal frequencies and luminances. We have also evaluated the responses at luminance levels at which the transition between rod- and cone-dominated responses occurs. This transition between rod- and cone-dominated flicker ERG responses is indicated by a significant change in the response characteristics between 4 and 8 cd/m(2) (between 200 and 400 phot Td). The findings on the transition between rod- and cone-dominated ERGs along with the demonstration of ERG responses to different temporal flicker modulations might be informative for the electrophysiologists when setting up the stimulus at mesopic and photopic luminance levels. (AU)

• Processo FAPESP: 09/54292-7 - Avaliacao do desempenho visual em diferentes condicoes de iluminacao artificial com caracteristicas espectrais variadas
• Beneficiário: Balazs Vince Nagy
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 08/58731-2 - A visão como indicador de processos lesivos na retina e no sistema nervoso central
• Beneficiário: Dora Selma Fix Ventura
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 07/55125-1 - Avaliação eletrofisiológica e psicofísica das vias visuais on e off em jovens com Distrofia Muscular de Duchenne
• Beneficiário: Mirella Telles Salgueiro Barboni
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 12/51299-3 - International joint research on the development and application of electroretinographic and psychophysical methods for the assessment of postreceptoral on-and off-mechanisms in both chromatic and luminance retinal visual pathways in Duchenne muscular dystrophy and in Diabetes mellitus
• Beneficiário: Dora Selma Fix Ventura
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 12/01115-3 - Desenvolvimento e aplicação de métodos eletroretinográficos e psicofísicos para avaliação de mecanismos on e off nas vias visuais de luminância e de oponência cromática na Diabetes Mellitus e na distrofia muscular de Duchenne
• Beneficiário: Dora Selma Fix Ventura
• Modalidade de apoio: Auxílio à Pesquisa - Regular