Effect of particles of ashes produced from sugarcane burning on the respiratory system of rats

Autor(es)

Ferreira, L. E. N. ^[1] ; Muniz, B. V. ^[1] ; Bittar, T. O. ^[2] ; Berto, L. A. ^[1] ; Figueroba, S. R. ^[1] ; Groppo, F. C. ^[1] ; Pereira, A. C. ^[2]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, UNICAMP, Piracicaba Dent Sch, Dept Physiol Sci, Sao Paulo - Brazil

^[2] Univ Estadual Campinas, UNICAMP, Piracicaba Dent Sch, Dept Social Dent, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Environmental Research; v. 135, p. 304-310, NOV 2014.
• Citações Web of Science: 2

Resumo

The practice of burning sugarcane obtained by non-mechanized harvesting exposes workers and the people of neighboring towns to high concentrations of particulate matter (PM) that is harmful to health, and may trigger a series of cardiorespiratory diseases. The aim of this study was to analyze the chemical composition of the micro-particles coming from sugarcane burning residues and to verify the effects of this micro-particulate matter on lung and tracheal tissues. Micro-particulate matter (PM10) was obtained by dissolving filter paper containing burnt residues in NaCl solution. This material was instilled into the Wistar rats' nostrils. Histological analyses (hematoxylin and eosin - HE) of cardiac, lung and tracheal tissues were performed. Inflammatory mediators were measured in lung tissues by using ELISA. The chemical composition of the particulate material revealed a large quantity of the phthalic acid ester, high concentrations of phenolic compounds, anthracene and polycyclic aromatic hydrocarbons (PAH). Histological analysis showed a reduction in subjacent conjunctive tissue in the trachea, lung inflammation with inflammatory infiltrate formation and reduction of alveolar spaces and a significant increase (p < 0.05) in the release of IL-1 alpha, IL-1 beta, IL-6, and INF-gamma in the group treated with PM10 when compared to the control group. We concluded that the burning sugarcane residues release many particles, which have toxic chemical compounds. The micro-particulate matter can induce alterations in the respiratory system. (C) 2014 Elsevier Inc. All rights reserved. (AU)

• Processo FAPESP: 08/02767-9 - Estudo epidemiológico-experimental dos efeitos do material particulado proveniente da combustão da biomassa das lavouras de cana-de-açúcar sobre a saúde humana e animal
• Beneficiário: Antonio Carlos Pereira
• Modalidade de apoio: Auxílio à Pesquisa - Regular