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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of particles of ashes produced from sugarcane burning on the respiratory system of rats

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Author(s):
Ferreira, L. E. N. [1] ; Muniz, B. V. [1] ; Bittar, T. O. [2] ; Berto, L. A. [1] ; Figueroba, S. R. [1] ; Groppo, F. C. [1] ; Pereira, A. C. [2]
Total Authors: 7
Affiliation:
[1] Univ Estadual Campinas, UNICAMP, Piracicaba Dent Sch, Dept Physiol Sci, Sao Paulo - Brazil
[2] Univ Estadual Campinas, UNICAMP, Piracicaba Dent Sch, Dept Social Dent, Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Environmental Research; v. 135, p. 304-310, NOV 2014.
Web of Science Citations: 2
Abstract

The practice of burning sugarcane obtained by non-mechanized harvesting exposes workers and the people of neighboring towns to high concentrations of particulate matter (PM) that is harmful to health, and may trigger a series of cardiorespiratory diseases. The aim of this study was to analyze the chemical composition of the micro-particles coming from sugarcane burning residues and to verify the effects of this micro-particulate matter on lung and tracheal tissues. Micro-particulate matter (PM10) was obtained by dissolving filter paper containing burnt residues in NaCl solution. This material was instilled into the Wistar rats' nostrils. Histological analyses (hematoxylin and eosin - HE) of cardiac, lung and tracheal tissues were performed. Inflammatory mediators were measured in lung tissues by using ELISA. The chemical composition of the particulate material revealed a large quantity of the phthalic acid ester, high concentrations of phenolic compounds, anthracene and polycyclic aromatic hydrocarbons (PAH). Histological analysis showed a reduction in subjacent conjunctive tissue in the trachea, lung inflammation with inflammatory infiltrate formation and reduction of alveolar spaces and a significant increase (p < 0.05) in the release of IL-1 alpha, IL-1 beta, IL-6, and INF-gamma in the group treated with PM10 when compared to the control group. We concluded that the burning sugarcane residues release many particles, which have toxic chemical compounds. The micro-particulate matter can induce alterations in the respiratory system. (C) 2014 Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 08/02767-9 - Epidemiological and experimental study of the effects from sugar-cane particulate matter crops combustion over human and animal health
Grantee:Antonio Carlos Pereira
Support Opportunities: Regular Research Grants