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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Computerized fetal heart rate analysis in the prediction of myocardial damage in pregnancies with placental insufficiency

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Autor(es):
Maeda, Mariane de Fatima Y. [1] ; Nomura, Roseli M. Y. [1] ; Niigaki, Juliana I. [1] ; Francisco, Rossana P. V. [1] ; Zugaib, Marcelo [1]
Número total de Autores: 5
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Sch Med, Dept Obstet & Ginecol, BR-05403000 Sao Paulo, SP - Brazil
Número total de Afiliações: 1
Tipo de documento: Artigo Científico
Fonte: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY; v. 190, p. 7-10, JUL 2015.
Citações Web of Science: 1
Resumo

Objective: To evaluate the reliability of fetal heart rate (FHR) parameters analyzed by computerized cardiotocography (cCTG) in predicting myocardial damage in pregnancies with placental insufficiency. Study design: We evaluated 38 patients with placental insufficiency detected before 34 weeks of gestation. All patients underwent 30 min of cCTG (Sonicaid Fetal Care, version 2.2) and Doppler of umbilical artery, middle cerebral artery, and ductus venosus. Umbilical vein blood samples were collected at birth to determine fetal cardiac Troponin T, and a >= 0.09 ng/ml value was deemed a sign of myocardial damage. Results: The fetuses with myocardial damage (39%) showed significantly increased values of umbilical artery pulsatility index z-score (P = 0.003), ductus venosus pulsatility index z-score (P = 0.007), basal FHR (P = 0.033) and periods of low episodes (P = 0.038). The number of small accelerations and the short-term variation (STV) were significantly reduced in the group with myocardial damage (P = 0.013 and P = 0.003, respectively). Logistic regression analysis identified SW and gestational age at delivery as independent predictors for fetal myocardial damage, with area under ROC curve of 0.91. Conclusions: Computerized cardiotocography parameters may be useful in the management of early onset placental insufficiency, and the association of SW with gestational age could play a role in detecting myocardial injury in pregnancies with placental insufficiency. (C) 2015 Elsevier Ireland Ltd. All rights reserved. (AU)

Processo FAPESP: 10/19873-6 - Cardiotocografia computadorizada e dano cardíaco fetal em gestações com insuficiência placentária
Beneficiário:Roseli Mieko Yamamoto Nomura
Linha de fomento: Auxílio à Pesquisa - Regular