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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Computerized fetal heart rate analysis in the prediction of myocardial damage in pregnancies with placental insufficiency

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Author(s):
Maeda, Mariane de Fatima Y. [1] ; Nomura, Roseli M. Y. [1] ; Niigaki, Juliana I. [1] ; Francisco, Rossana P. V. [1] ; Zugaib, Marcelo [1]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, Sch Med, Dept Obstet & Ginecol, BR-05403000 Sao Paulo, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY; v. 190, p. 7-10, JUL 2015.
Web of Science Citations: 1
Abstract

Objective: To evaluate the reliability of fetal heart rate (FHR) parameters analyzed by computerized cardiotocography (cCTG) in predicting myocardial damage in pregnancies with placental insufficiency. Study design: We evaluated 38 patients with placental insufficiency detected before 34 weeks of gestation. All patients underwent 30 min of cCTG (Sonicaid Fetal Care, version 2.2) and Doppler of umbilical artery, middle cerebral artery, and ductus venosus. Umbilical vein blood samples were collected at birth to determine fetal cardiac Troponin T, and a >= 0.09 ng/ml value was deemed a sign of myocardial damage. Results: The fetuses with myocardial damage (39%) showed significantly increased values of umbilical artery pulsatility index z-score (P = 0.003), ductus venosus pulsatility index z-score (P = 0.007), basal FHR (P = 0.033) and periods of low episodes (P = 0.038). The number of small accelerations and the short-term variation (STV) were significantly reduced in the group with myocardial damage (P = 0.013 and P = 0.003, respectively). Logistic regression analysis identified SW and gestational age at delivery as independent predictors for fetal myocardial damage, with area under ROC curve of 0.91. Conclusions: Computerized cardiotocography parameters may be useful in the management of early onset placental insufficiency, and the association of SW with gestational age could play a role in detecting myocardial injury in pregnancies with placental insufficiency. (C) 2015 Elsevier Ireland Ltd. All rights reserved. (AU)

FAPESP's process: 10/19873-6 - Computerized cardiotocography and fetal cardiac injury in pregnancies with placental insufficiency
Grantee:Roseli Mieko Yamamoto Nomura
Support type: Regular Research Grants