Real-time characterization of the uterine blood flow in mares before and after artificial insemination

Autor(es)

Ferreira, J. C. ^[1] ; Ignacio, F. S. ^[1] ; Rocha, N. S. ^[2] ; Thompson, Jr., D. L. ^[3] ; Pinto, C. R. ^[4] ; Meira, C. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Paulista UNESP, Dept Anim Reprod & Vet Radiol, BR-18618970 Sao Paulo, SP - Brazil

^[2] Univ Estadual Paulista UNESP, Dept Vet Clin, BR-18618970 Sao Paulo, SP - Brazil

^[3] Louisiana State Univ, Sch Anim Sci, Baton Rouge, LA 70803 - USA

^[4] Louisiana State Univ, Sch Vet Med, Baton Rouge, LA 70803 - USA

• Tipo de documento: Artigo Científico
• Fonte: Animal Reproduction Science; v. 160, p. 90-96, SEP 2015.
• Citações Web of Science: 1

Resumo

The present experiment was divided into two studies to investigate the effect of age and endometrial degeneration on uterine blood flow of mares throughout the immediate post-breeding period. In study 1, uterine blood flow was characterized in mares (n = 7 mares/group) with minimal, moderate or severe endometrial degenerative changes (GI, GII and Gill, respectively). In study 2, the effect of age was investigated using young (<= 6 years) and old (>= 15 years) mares (n = 7 mares/group). Uterine vascular perfusion and mesometrial pulsatility index (PI) were evaluated every hour from H0 (moment immediately before AI) to H12. In study 1, a pronounced and transitory increase on uterine vascular perfusion was detected (P < 0.001) between H1 and H3 in the three endometrial groups. In addition, GIII mares had greater (P < 0.05) mesometrial PI than GI mares during the post-breeding period, denoting reduced uterine blood flow. In study 2, a transitory increase on uterine vascular perfusion was also observed in both age groups during the first hour after mating. However, mesometrial PI of young and old mares was similar (P > 0.05) and constant (P > 0.7) through the first 12 h after AI. Results demonstrated, for the first time, the immediate changes on uterine vascular perfusion and mesometrial PI in response to semen infusion. Moreover, reduced blood flow of the uterus during the post-breeding period was strongly associated with endometrial degenerative changes in mares, regardless of age. (C) 2015 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 09/52575-1 - Influência das alterações degenerativas endometriais na hemodinâmica do trato reprodutivo de éguas após a inseminação artificial e durante as fases iniciais do desenvolvimento embrionário
• Beneficiário: Jair Camargo Ferreira
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto
• Processo FAPESP: 08/54929-2 - Influencia das alteracoes degenerativas endometriais na hemodinamica do trato reprodutivo de eguas apos a inseminacao artificial e durante as fases iniciais do desenvolvimento embrionario.
• Beneficiário: Cezinande de Meira
• Modalidade de apoio: Auxílio à Pesquisa - Regular