Cardioprotective Properties of Aerobic and Resistance Training Against Myocardial Infarction

Autor(es)

Barboza, C. A. ^[1] ; Souza, G. I. H. ^[1] ; Oliveira, J. C. M. F. ^[1] ; Silva, L. M. ^[1] ; Mostarda, C. T. ^[2] ; Dourado, P. M. M. ^[3] ; Oyama, L. M. ^[4] ; Lira, F. S. ^[5] ; Irigoyen, M. C. ^[3] ; Rodrigues, B. ^[6]

Afiliação do(s) autor(es)

^[1] Univ Sao Judas Tadeu, Human Movement Lab, Sao Paulo, SP - Brazil

^[2] Univ Fed Maranhao, Hosp Materno Infantil, Sao Luis, MA - Brazil

^[3] Univ Sao Paulo, Sch Med, Inst Heart, Sao Paulo, SP - Brazil

^[4] Univ Fed Sao Paulo, Dept Fisiol, Sao Paulo, SP - Brazil

^[5] Univ Estadual Paulista, Exercise & Immunometab Res Grp, Dept Phys Educ, Presidente Prudente, SP - Brazil

^[6] Univ Campinas UNICAMP, Fac Phys Educ, Av Erico Verissimo 701, Cidade Univ, BR-13083851 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF SPORTS MEDICINE; v. 37, n. 6, p. 421-430, JUN 2016.
• Citações Web of Science: 5

Resumo

We evaluated the effects of aerobic and resistance exercise training on ventricular morphometry and function, physical capacity, autonomic function, as well as on ventricular inflammatory status in trained rats prior to myocardial infarction. Male Wistar rats were divided into the following groups: sedentary+Sham, sedentary+myocardial infarction, aerobic trained+myocardial infarction, and resistance trained+myocardial infarction. Sham and myocardial infarction were performed after training periods. In the days following the surgeries, evaluations were performed. Aerobic training prevents aerobic (to a greater extent) and resistance capacity impairments, ventricular dysfunction, baroreflex sensitivity and autonomic disorders (vagal tonus decrease and sympathetic tonus increase) triggered by myocardial infarction. Resistance training was able to prevent negative changes to aerobic and resistance capacity (to a greater extent) but not to ventricular dysfunction, and it prevented cardiovascular sympathetic increments. Additionally, both types of training reduced left ventricle inflammatory cytokine concentration. Our results suggest that aerobic and, for the first time, dynamic resistance training were able to reduce sympathetic tonus to the heart and vessels, as well as preventing the increase in pro-inflammatory cytokine concentrations in the left ventricle of trained groups. These data emphasizes the positive effects of aerobic and dynamic resistance training on the prevention of the negative changes triggered by myocardial infarction. (AU)

• Processo FAPESP: 13/14788-9 - Efeitos do treinamento físico associado à estimulação colinérgica por brometo de piridostigmina previamente e após o infarto do miocárdio: papel na função cardíaca, autonômica e no perfil inflamatório
• Beneficiário: Bruno Rodrigues
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 14/06669-2 - Treinamento físico aeróbico e resistido associado à estimulação colinérgica por brometo de piridostigmina previamente ao infarto do miocárdio em ratos: efeitos na função cardíaca, autonômica e perfil inflamatório
• Beneficiário: Catarina de Andrade Barboza
• Modalidade de apoio: Bolsas no Brasil - Doutorado