Electrodeposition and biomineralization of nano-beta-tricalcium phosphate on graphenated carbon nanotubes

Autor(es)

Metoki, N. ^[1] ; Rosa, C. M. R. ^[2] ; Zanin, H. ^[3] ; Marciano, F. R. ^[2] ; Eliaz, N. ^[1] ; Lobo, A. O. ^[2]

Afiliação do(s) autor(es)

^[1] Tel Aviv Univ, Dept Mat Sci & Engn, IL-6997801 Tel Aviv - Israel

^[2] Univ Vale Paraiba, Inst Res & Dev, Lab Biomed Nanotechnol Nanobio, Av Shishima Hifumi 2911, BR-12244000 Sao Jose Dos Campos, SP - Brazil

^[3] Univ Vale Paraiba, Inst Res & Dev, Lab Energy Storage & Supply ES&S, Av Shishima Hifumi 2911, BR-12244000 Sao Jose Dos Campos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: SURFACE & COATINGS TECHNOLOGY; v. 297, p. 51-57, JUL 15 2016.
• Citações Web of Science: 7

Resumo

Nano-calcium-phosphate (n-CaP) is an attractive, biocompatible material for increasing osteointegration. Among nanomaterials, functionalized carbon-based materials are emerging materials, which have excellent mechanical properties, biocompatibility and chemical stability. These properties may further enhance the n-CaP performance. It has been shown that stoichiometric n-CaP can be electrodeposited on graphene and carbon nanotubes (CNTs) by employing fast and low-cost electrodeposition techniques. Here, we present, for the first time, a crystalline, needle-like nano-beta-tricalcium phosphate (n-beta-TCP) electrodeposited on reduced graphene oxide (rGO) nanosheets. The rGO was grown on CNT, as a composite biomaterial, in a one-step process, followed by electrodeposition of n-CaP. The results show that, in acidic pH, needle-like crystals appear on the surface. It is speculated that the carboxyl (carboxylic acid)/carboxylate functional groups attached directly to the rGO are essential in accelerating OH- formation and deposition of needle-like n-CaP crystals. High-resolution scanning electron microscopy, transmission electron microscopy, energy dispersive X-ray spectroscopy, and X-ray diffraction elucidated homogeneous, highly crystalline, n-CaP (beta-tricalcium phosphate) crystals. This composite presented an excellent in vitro biomineralization after soaking in simulated body fluid. (C) 2016 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 11/20345-7 - Estudo de filmes de carbono-tipo diamante contendo nanopartículas incorporadas para aplicações biomédicas
• Beneficiário: Fernanda Roberta Marciano
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 13/09684-0 - Estudo de parâmetros para a eletrodeposição de hidroxiapatita sobre nanotubos de carbono alinhados visando aplicações como arcabouços para crescimento ósseo
• Beneficiário: Cintia Maria Rodrigues Rosa
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica
• Processo FAPESP: 11/17877-7 - Desenvolvimento de novos scaffolds poliméricos por eletrofiação com incorporação de nanotubos alinhados e nanohidroxiapatita para regeneração óssea
• Beneficiário: Anderson de Oliveira Lobo
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores