Process intensification for producing powdered extracts rich in bioactive compounds: An economic approach

Autor(es)

Zabot, Giovani L. ; Bitencourte, Iuri P. ; Tres, Marcus V. ; Meireles, M. A. A.

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF SUPERCRITICAL FLUIDS; v. 119, p. 261-273, JAN 2017.
• Citações Web of Science: 8

Resumo

The hyphenated on-line association of pressurized liquid extraction (PLE) with supercritical antisolvent (SAS) precipitation was performed in sequential mode to obtain quercetin-rich powdered extracts from onion peels. The PLE performed at 40 degrees C and 12 MPa with ethanol and the SAS performed at 40 degrees C and 1 0 MPa with supercritical CO2 provided 4.1 +/- 0.6 g microparticles/100 g onion peels with 26 +/- 2 wt.% (mass basis) of quercetin, which the microparticles presented a mean particle diameter equal to 119 +/- 1 mu m. The proposed process was then evaluated in the economic aspect with the objective to show its feasibility in different scenarios. Among the 40 scenarios assessed, the more promising one in the techno-economic viewpoint is indicated in the larger plant capacity, with vessels of 500 L. For a productivity of 17.7 ton/year, the cost of manufacturing (COM) the microparticles was only US\$ 63.98/kg. In such scenario, the return on investment, the payback time, and the gross margin were 120.8%, 0.8 years and 82.2%, respectively. The COM of powdered extracts is low because the acquisition cost of onion peels (food waste) is null. The main components that influence the COM are the fixed capital of investment (53-59%) and the cost of utilities (10-22%). The economic findings demonstrate that the process intensification (PLE + SAS) is a profitable alternative because the pressure energy applied in the extraction vessel can be used as useful energy for spraying and producing microparticles in the precipitation vessel. (C) 2016 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 14/15685-1 - Intensificação de processos para obtenção de extratos naturais e formação de partículas on-line usando tecnologia supercrítica
• Beneficiário: Giovani Leone Zabot
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 12/10685-8 - Combinação/acoplamento de processos para a produção e encapsulamento de extratos vegetais de alto valor agregado: avaliação técnica e econômica
• Beneficiário: Maria Angela de Almeida Meireles Petenate
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 15/13299-0 - Das sementes aos produtos finais: rotas possíveis de manufatura de Urucum aplicando intensificação e integração de processos
• Beneficiário: Maria Angela de Almeida Meireles Petenate
• Modalidade de apoio: Auxílio à Pesquisa - Regular