| Texto completo | |
| Autor(es): |
Shamim, Anwar
;
Souza, Frederico B.
;
Vasconcelos, Stanley N. S.
;
Stefani, Helio A.
Número total de Autores: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Tetrahedron Letters; v. 58, n. 9, p. 884-888, MAR 1 2017. |
| Citações Web of Science: | 6 |
| Resumo | |
A library of glucal-derived triazoles have been synthesized using the copper-catalyzed azide-alkyne cyclization reaction starting from 3,4,6-tri-O-acetyl-h-glucal. Different trimethylsilyl substituted alkyne derivatives of glucal were first synthesized from 3,4,6-tri-O-acetyl-D-glucal, using Sonogashira coupling, hydrostannation and iodination steps. These glucal-based trimethylsilyl-protected alkynes were then used in the copper-catalyzed cyclization reactions with different organic azides to synthesize the corresponding triazole derivatives of D-glucal. (C) 2017 Elsevier Ltd. All rights reserved. (AU) | |
| Processo FAPESP: | 12/00424-2 - Síntese de pequenas bibliotecas empregando organotrifluoroboratos de potássio em reações de Suzuki-Miyaura |
| Beneficiário: | Helio Alexandre Stefani |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |