Evaluation of the influence of clinical symptoms on the quality of life in individuals with Williams-Beuren Syndrome

Autor(es)

Graziani, Luisa de Mattos ; Jackowski, Andrea Parolin ; Salvador Rossit, Rosana Aparecida ; Del Cole, Carolina Grego

• Tipo de documento: Artigo Científico
• Fonte: CADERNOS DE TERAPIA OCUPACIONAL DA UFSCAR; v. 25, n. 1, p. 125-135, 2017.
• Citações Web of Science: 1

Resumo

Introduction: Williams-Beuren Syndrome (WBS) results from a deletion in the chromosome 7q11.23. Psychiatric symptoms, such as Generalized Anxiety Disorder (GAD), Attention Deficit Hyperactivity Disorder (ADHD), and others, have been described in this syndrome. Objective: The main purpose of this study was to identify related clinical symptoms in individuals with WBS and the impact of this disorder in their quality of life. Method: The study sample included 42 individuals aged 11 to 16 years divided into two groups: a study group composed of 20 individuals with WBS and a control group comprising 22 individuals with typical development. The following instruments were used in this evaluation: Brazilian Criterion of Economic Classification (CCEB), to estimate the purchasing power of urban households; Strengths \& Difficulties Questionnaire (SDQ), to provide a useful measure of psychopathology applied to children and youth aged 4-17 years; and Quality of Life Evaluation Scale (AUQEI), to assess the feeling of well-being according to the opinion of the child and adolescent. Results: The results suggest that adolescents with WBS have a good quality of life despite presenting greater possibilities of psychiatric symptoms. These results are valid considering that quality of life is measured from the opinion of the assessed individual. Conclusion: We hypothesized that adolescents with WBS can present a distortion of reality regarding the positive/optimistic factor, possibly based on some characteristics of the syndrome such as being always cheerful and smiling, which are factors associated with intellectual disability. (AU)

• Processo FAPESP: 11/19421-0 - Avaliação dos Transtornos Psiquiátricos dos indivíduos com Síndrome de Williams-Beuren e suas consequências no cotidiano
• Beneficiário: Luísa de Mattos Graziani
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica