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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

A Perspective Discussion on Rising Pesticide Levels and Colon Cancer Burden in Brazil

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Autor(es):
Uyemura, Sergio Akira [1] ; Stopper, Helga [2] ; Martin, Francis L. [3] ; Kannen, Vinicius [1]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Dept Toxicol Bromatol & Clin Anal, Ribeirao Preto - Brazil
[2] Univ Wurzburg, Dept Toxicol, Wurzburg - Germany
[3] Univ Cent Lancashire, Sch Pharm & Biomed Sci, Preston, Lancs - England
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: FRONTIERS IN PUBLIC HEALTH; v. 5, OCT 16 2017.
Citações Web of Science: 3
Resumo

Agriculture is a mainstay of many developing countries' economy, such as Brazil. According to the Food and Agriculture Organization of the United Nations, Brazil is the major global consumer of pesticides. Irrespective of the fact that the International Agency for Research on Cancer suggests that pesticides promote human cancer risk, a prospective study reports that colorectal cancer (CRC) burden will increase in developing countries by approximately 60% in the coming decades. Here, we review the literature and public data from the Brazilian Federal Government to explore why pesticides levels and new cases of colon cancer (CC) are rising rapidly in the country. CC incidence is the second most common malignancy in men and women in the South and the Southeast of Brazil. However, while these regions have almost doubled their pesticide levels and CC mortality in 14 years, the amount of sold pesticides increased 5.2-fold with a corresponding 6.2-fold increase in CC mortality in Northern and Northeastern states. Interestingly, mortality from endocrine, nutritional, and metabolic diseases are rapidly increasing, in close resemblance with the pesticide detection levels in food. Taken together, we discuss the possibility that pesticides might alter the risk of CC. (AU)

Processo FAPESP: 14/06428-5 - Como a sinalização serotoninérgica epitelial difere dos efeitos de sua síntese neural durante a inflamação associada ou não ao câncer de cólon
Beneficiário:Vinicius Kannen Cardoso
Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
Processo FAPESP: 15/01723-1 - Como a sinalização serotoninérgica epitelial difere dos efeitos de sua síntese neural durante a carcinogênese de cólon
Beneficiário:Vinicius Kannen Cardoso
Modalidade de apoio: Bolsas no Brasil - Jovens Pesquisadores