Use of Non-Invasive Ventilation in Children and Adolescents: Scientific Evidence

Autor(es)

Goncalves Bonaldo, Taisa Crespi ^[1] ; Souza Gomez, Carla Cristina ^[1] ; Francisco Parazzi, Paloma Lopes ^[1] ; Bresciani Almeida, Celize Cruz ^[1] ; Lima Marson, Fernando Augusto ^{[1, 2]} ; de Oliveira, Therezinha ^[1] ; Alves Grande, Rosangela Aparecida ^[1] ; Cohen, Milena Antonelli ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Dept Pediat, Tessalia Vieira de Camargo 126, BR-13083887 Sao Paulo - Brazil

^[2] Univ Estadual Campinas, Dept Med Genet, Tessalia Vieira de Camargo 126, BR-13083887 Sao Paulo - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: CURRENT RESPIRATORY MEDICINE REVIEWS; v. 13, n. 2, p. 82-92, 2017.
• Citações Web of Science: 0

Resumo

Background: Noninvasive ventilation (NIV) is a method of positive pressure ventilation that does not require an endotracheal tube. NIV is used in pediatrics in numerous clinical conditions, but it is necessary to systematize the available knowledge to better understand its application and effectiveness in disease management. Objective: To discuss the scientific evidence published in the last five years (2011 to 2016) regarding the use of NIV in children and adolescents. Methods: A systematic review was performed in the databases PEDro and MEDLINE using the descriptors: noninvasive ventilation, pediatrics, children and adolescent. We selected articles with participants aged from zero to 20 years, regardless of pathology, who were submitted to NIV in the hospital or at home. We excluded studies that did not have the assessment of NIV as the main objective. Results: Initially, 377 articles were identified, of these, 123 articles were excluded because of the title, year or duplicity, 147 because of the abstract, and 73 after full reading. Thus, 34 articles were included in the review. Of the 34 articles evaluated, only two reported side effects for NIV, but the benefits outweigh the side effects mentioned. Conclusion: NIV has become a reality well established and studied in pediatrics in numerous diseases. In the review, we demonstrated that NIV is safe, viable and effective for the treatment of acute respiratory failure, obstructive sleep apnea syndrome, nocturnal alveolar hypoventilation, acute viral bronchiolitis, neuromuscular disease, asthma and cystic fibrosis, and that it can be used as therapy at home. (AU)

• Processo FAPESP: 11/12939-4 - Associação entre polimorfismos de genes moduladores em crianças e adolescentes com asma alérgica e não alérgica: leve, moderada e grave
• Beneficiário: Fernando Augusto de Lima Marson
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 15/12183-8 - Identificação das mutações prevalentes e caracterização clínica e funcional de crianças e adultos com discinesia ciliar primária
• Beneficiário: Jose Dirceu Ribeiro
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 11/18845-1 - Associação entre polimorfismos de genes moduladores em crianças e adolescentes com asma alérgica e não alérgica leve, moderada e grave
• Beneficiário: Jose Dirceu Ribeiro
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 15/12858-5 - Identificação das mutações prevalentes e caracterização clínica e funcional de crianças e adultos com discinesia ciliar primária
• Beneficiário: Fernando Augusto de Lima Marson
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado