Is there a place for dexmedetomidine in equine anaesthesia and analgesia? A systematic review (2005-2017)

Autor(es)

Gozalo-Marcilla, M. ^[1] ; Gasthuys, F. ^[2] ; Luna, S. P. L. ^[1] ; Schauvliege, S. ^[2]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ UNESP, Dept Vet Surg & Anaesthesiol, Sch Vet Med & Anim Sci, Botucatu, SP - Brazil

^[2] Univ Ghent, Dept Surg & Anaesthesia Domest Anim, Fac Vet Med, Merelbeke - Belgium

• Tipo de documento: Artigo de Revisão
• Fonte: JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; v. 41, n. 2, p. 205-217, APR 2018.
• Citações Web of Science: 5

Resumo

The objective of this review was to perform a literature compilation of all the equine publications that used dexmedetomidine as the first article on this topic was published, in 2005. We also aimed to answer the question whether the use of dexmedetomidine can currently be justified. For that, we compiled information from databases, such as PubMed, Google Scholar and Web of Science and the proceedings of the last veterinary anaesthesiology meetings. Dexmedetomidine is an attractive drug to be used in horses, mainly due to its pharmacokinetic profile and pharmacodynamics that favour its use as intravenous constant rate infusion (CRI). Nowadays, its clinical use is popular for sedation in prolonged standing procedures and during partial intravenous anaesthesia (PIVA) and total intravenous anaesthesia (TIVA). However, legal requirements for its use should be taken into account. (AU)

• Processo FAPESP: 17/01425-6 - Aplicação clínica de diferentes taxas de infusão de detomidina e metadona em cavalos em estação.
• Beneficiário: Miguel Gozalo Marcilla
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Pós-Doutorado
• Processo FAPESP: 14/00474-5 - Efeitos antinociceptivos e farmacocinética em equinos tratados com diferentes doses baixas de metadona e detomidina
• Beneficiário: Miguel Gozalo Marcilla
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado