Polycystic Ovary Syndrome among Obese Adolescents

Autor(es)

Ybarra, Marina ^[1] ; Franco, Ruth Rocha ^[1] ; Cominato, Louise ^[1] ; Sampaio, Raissa Beltrao ^[1] ; Sucena da Rocha, Silvia Maria ^[2] ; Damiani, Durval ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Pediat Endocrinol Unit, Inst Crianca, Hosp Clin, Fac Med, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Pediat Radiol Unit, Inst Crianca, Hosp Clin, Fac Med, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Gynecological Endocrinology; v. 34, n. 1, p. 45-48, 2018.
• Citações Web of Science: 4

Resumo

Background and aims: In adolescence and obesity, the pathophysiology of polycystic ovary syndrome (PCOS) is very difficult to distinguish. We aimed to assess the diagnosis of PCOS in the population of obese adolescent. Methods: Cross-sectional study. Setting: Pediatric Endocrinology Weight and Management Clinic from Children's Institute, Sao Paulo, Brazil. Participants: Forty-nine post-menarcheal obese adolescents with mean age of 14.7 years. Interventions: Anthropometric assessment and review of medical records were done. Clinical and laboratory hyperandrogenism were quantified using Ferriman-Gallwey index and androgenic dosages, respectively. Ovarian morphology was evaluated through suprapubic ultrasonography. Results: By the 2015 Witchel et al. guideline for PCOS in adolescence, 18.4% were diagnosed as having PCOS. When assessed by Rotterdam, Androgen Excess and PCOS Society, and American National Institute of Health criteria's, 26.4%, 22.4%, and 20.4% had PCOS, respectively. Irregular menstrual cycles were found in 65.3% of patients. Clinical hyperandrogenism was observed in 16.3% of girls and 18.4% had elevated serum androgen values. Suprapubic ultrasonography revealed enlarged ovaries in 18.4% of the adolescents. Conclusions: PCOS in all-comers obese adolescents from a Weight and Management Clinic in a quaternary hospital is more frequent when compared to adult women showed in the literature. (AU)

• Processo FAPESP: 14/11200-3 - Avaliação da prevalência e das características da síndrome do ovário policístico em adolescentes obesas
• Beneficiário: Marina Pereira Ybarra Martins de Oliveira
• Modalidade de apoio: Bolsas no Brasil - Mestrado