Enhancing bond strength on demineralized dentin by pre-treatment with selective remineralising agents

Autor(es)

Barbosa-Martins, Luiz Filipe ^[1] ; de Sousa, Jossaria Pereira ^[1] ; Freire de Castilho, Aline Rogeria ^[1] ; Puppin-Rontani, Julia ^[2] ; Davies, Robert P. W. ^[3] ; Puppin-Rontani, Regina Maria ^{[1, 2]}

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Pediat Dent, 901 Limeira Ave, BR-13414903 Sao Paulo - Brazil

^[2] Univ Estadual Campinas, Dept Restorat Dent, Sao Paulo - Brazil

^[3] Univ Leeds, Dept Oral Biol, St James Univ Hosp, Leeds, W Yorkshire - England

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS; v. 81, p. 214-221, MAY 2018.
• Citações Web of Science: 4

Resumo

Bonding to demineralized dentin of a diseased tooth has shown to be a significant clinical issue. This study evaluated the effect of 0.2% NaF-(NaF), MI Paste (TM)-(CPP-ACP) and the self-assembling peptide `P11-4' (Ace-QQRFEWEFEQQ-NH2) contained in Curodont (TM) Repair, have on microtensile bond strength-(mu TBS) of two different adhesive systems (Adper (TM) Single Bond-(SB) or Clearfil (TM) SE Bond (CSE)) and wettability of demineralized dentin slices after remineralising agents were applied. The highest mu TBS were found for the demineralized dentin-(DD) treated with CPP-ACP; both adhesives systems (p < 0.05) did not significantly difference from P11-4 treatment associated with SB, and also presented higher values than sound dentin-(SD/SB) (p < 0.01). DD treated with P11-4 associated with CSE did not differ from DD/CSE (p > 0.05). The NaF treatment associated with CSE recovered the bond strength values of SD/CSE and associated with CSE demonstrated lower mu TBS than other groups, although significantly higher than DD (p < 0.05). P11-4 and CPP-ACP increased significantly the wettability of demineralized dentin (p < 0.05); etching acid improved wettability for all groups (p < 0.05), whilst NaF did not affect the wettability of demineralized dentin (p > 0.05). Morphological analysis of the dentin surface and dentin-resin interface revealed unique features of the applied remineralizing agent. The results indicated that self-assembling peptide P11-4 associated with SB and CPP-ACP associated with SB or CSE significantly enhanced the bond strength to demineralized dentin (p < 0.05). We conclude that by modifying the dentine surface and restoring conditions found on sound dentin, this can enhance the interfacial bonding. (AU)

• Processo FAPESP: 15/12660-0 - Estudo da ação de agentes remineralizadores na atividade proteolítica e na longevidade da união resina/dentina humana afetada por cárie
• Beneficiário: Regina Maria Puppin Rontani
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 11/16634-3 - Avaliação da resistência de união a dentina afetada por cárie pós-tratamento por diferentes substâncias com capacidade remineralizadora
• Beneficiário: Luiz Filipe Barbosa Martins
• Modalidade de apoio: Bolsas no Brasil - Mestrado