Comparative analysis of in vitro antioxidant capacities of mycosporine-like amino acids (MAAs)

Autor(es)

Torres, Priscila ^[1] ; Santos, Janaina Pires ^[2] ; Chow, Fungyi ^[2] ; Pena Ferreira, Marcelo J. ^[1] ; dos Santos, Deborah Y. A. C. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Biosci, Dept Bot, Phytochem Lab, Sao Paulo, SP - Brazil

^[2] Univ Sao Paulo, Inst Biosci, Dept Bot, Lab Marine Algae Edison Jose de Paula, Sao Paulo, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS; v. 34, p. 57-67, SEP 2018.
• Citações Web of Science: 8

Resumo

The most common Mycosporine-like Amino Acids (MAAs) in red algae (asterina-330, shinorine, palythine, palythinol, and porphyra-334) were evaluated regarding their in vitro antioxidant capacities, comparing them with synthetic (BHT and Trolox) and natural (ascorbic acid, gallic acid, p-cumaric acid, quercetin, and rutin) antioxidants. Folin-Ciocalteu, ABTS center dot(+), and FRAP assays have the same reaction mechanism of electron transfer and usually show a positive correlation. However, the antioxidant capacities for the MAAs were discrepant between these assays. While porphyra-334, shinorine, and palythine were as active as, or more active than synthetic phenolic antioxidants (Trolox and BHT) in Folin-Ciocalteu assay, the antioxidant potentials of MAAs were lower than those of the standard compounds in ABTS center dot(+) and FRAP assays. The pH-dependent antioxidant power was hypothesized as an explanation for this distinct behavior and was evaluated through ABTS center dot(+) assay. Alkaline pH allows antioxidant capacities similar to Trolox in ABTS center dot(+) assay, supporting our hypothesis. Comparing to standard compounds, MAAs showed low activity using ORAC assay and were pro-oxidant in beta-carotene/linoleic acid assay. Therefore, imino-MAAs present relevant in vitro antioxidant capacity under specific pH conditions in assays based on electron transfer. (AU)

• Processo FAPESP: 13/07543-0 - Atividades pesticida de acetogeninas de espécies de Annonaceae nativas do Cerrado
• Beneficiário: Déborah Yara Alves Cursino dos Santos
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 13/50731-1 - Biodiversidade fisiológica e química de macroalgas ecológica e economicamente importantes
• Beneficiário: Fanly Fungyi Chow Ho
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Regular