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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Comparative analysis of in vitro antioxidant capacities of mycosporine-like amino acids (MAAs)

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Author(s):
Torres, Priscila [1] ; Santos, Janaina Pires [2] ; Chow, Fungyi [2] ; Pena Ferreira, Marcelo J. [1] ; dos Santos, Deborah Y. A. C. [1]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, Inst Biosci, Dept Bot, Phytochem Lab, Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Inst Biosci, Dept Bot, Lab Marine Algae Edison Jose de Paula, Sao Paulo, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS; v. 34, p. 57-67, SEP 2018.
Web of Science Citations: 7
Abstract

The most common Mycosporine-like Amino Acids (MAAs) in red algae (asterina-330, shinorine, palythine, palythinol, and porphyra-334) were evaluated regarding their in vitro antioxidant capacities, comparing them with synthetic (BHT and Trolox) and natural (ascorbic acid, gallic acid, p-cumaric acid, quercetin, and rutin) antioxidants. Folin-Ciocalteu, ABTS center dot(+), and FRAP assays have the same reaction mechanism of electron transfer and usually show a positive correlation. However, the antioxidant capacities for the MAAs were discrepant between these assays. While porphyra-334, shinorine, and palythine were as active as, or more active than synthetic phenolic antioxidants (Trolox and BHT) in Folin-Ciocalteu assay, the antioxidant potentials of MAAs were lower than those of the standard compounds in ABTS center dot(+) and FRAP assays. The pH-dependent antioxidant power was hypothesized as an explanation for this distinct behavior and was evaluated through ABTS center dot(+) assay. Alkaline pH allows antioxidant capacities similar to Trolox in ABTS center dot(+) assay, supporting our hypothesis. Comparing to standard compounds, MAAs showed low activity using ORAC assay and were pro-oxidant in beta-carotene/linoleic acid assay. Therefore, imino-MAAs present relevant in vitro antioxidant capacity under specific pH conditions in assays based on electron transfer. (AU)

FAPESP's process: 13/07543-0 - Pesticide activities of acetogenins of native species of Annonaceae from Brazilian Savanna
Grantee:Déborah Yara Alves Cursino dos Santos
Support type: Regular Research Grants
FAPESP's process: 13/50731-1 - Physiological and chemical biodiversity of macroalgae ecologically and economically important
Grantee:Fanly Fungyi Chow Ho
Support type: BIOTA-FAPESP Program - Regular Research Grants