| Texto completo | |
| Autor(es): |
Machado de Rezende, Leandro Fornias
[1]
;
Totaro Garcia, Leandro Martin
[2]
;
Mielke, Gregore Iven
[3, 4]
;
Lee, Dong Hoon
[5]
;
Wu, Kana
[5]
;
Giovannucci, Edward
[6, 7, 5, 8]
;
Eluf-Neto, Jose
[1]
Número total de Autores: 7
|
| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Fac Med FMUSP, Dept Med Prevent, Sao Paulo, SP - Brazil
[2] Univ Cambridge, Sch Clin Med, MRC Epidemiol Unit, UKCRC Ctr Diet & Act Res, Cambridge - England
[3] Univ Fed Pelotas, Postgrad Program Epidemiol, Pelotas, RS - Brazil
[4] Univ Queensland, Sch Human Movement & Nutr Sci, Brisbane, Qld - Australia
[5] Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA - USA
[6] Harvard Med Sch, Boston, MA - USA
[7] Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA - USA
[8] Brigham & Womens Hosp, Channing Div Network Med, 75 Francis St, Boston, MA 02115 - USA
Número total de Afiliações: 8
|
| Tipo de documento: | Artigo Científico |
| Fonte: | CANCER EPIDEMIOLOGY; v. 56, p. 38-45, OCT 2018. |
| Citações Web of Science: | 1 |
| Resumo | |
Background: Physical activity is associated with lower risk of colon and breast cancers. Herein we estimated preventable fractions of colon and breast cancers in Brazil by increasing population-wide physical activity to different counterfactual scenarios. Methods: We used data from a representative national survey in Brazil and corresponding relative risks of colon and postmenopausal breast cancers from a meta-analysis. Estimated cancer incidence was retrieved from GLOBOCAN and Brazilian National Cancer Institute. Five counterfactual scenarios for physical activity were considered: (i) theoretical minimum risk exposure level (>= 8,000 metabolic equivalent of tasks-minute/week-MET-min/week); (ii) physical activity recommendation (>= 600 MET-min/week); (iii) a 10% reduction in prevalence of insufficient physical inactivity (< 600 MET-min/week); (iv) physical activity level in each state equals the most active state in Brazil; (v) closing the gender differences in physical activity. Results: About 19% (3,630 cases) of colon cancers and 12% (6,712 cases) of postmenopausal breast cancers could be prevented by increasing physical activity to >= 8,000 MET-min/week. Plausible counterfactual scenarios suggested the following impact on cancer prevention: reaching physical activity recommendation: 1.7% (1,113 cases) of breast and 6% (1,137 cases) of colon; 10% reduction in physical inactivity prevalence: 0.2% (111 cases) of breast and 0.6% (114 cases) of colon; most active state scenario: 0.3% (168 cases) of breast and 1% (189 cases) of colon; reducing gender differences in physical activity: 1.1% (384 cases) of breast and 0.6% (122 cases) of colon. Conclusions: High levels of physical activity are required to achieve a sizable impact on breast and colon cancer prevention in Brazil. (AU) | |
| Processo FAPESP: | 16/21390-0 - Carga do câncer atribuível ao estilo de vida no Brasil |
| Beneficiário: | Leandro Fórnias Machado de Rezende |
| Modalidade de apoio: | Bolsas no Exterior - Estágio de Pesquisa - Doutorado |
| Processo FAPESP: | 14/25614-4 - Inatividade física e câncer: da avaliação da evidência etiológica ao impacto na saúde pública |
| Beneficiário: | Leandro Fórnias Machado de Rezende |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |