The Role of Inflammation and Immune Cells in Blood Flow Restriction Training Adaptation: A Review

Autor(es)

Rossi, Fabricio Eduardo ^[1] ; de Freitas, Marcelo Conrado ^[2] ; Zanchi, Nelo Eidy ^[3] ; Lira, Fabio Santos ^[1] ; Cholewa, Jason M. ^[4]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ UNESP, Dept Phys Educ, Exercise & Immunometab Res Grp, Presidente Prudente - Brazil

^[2] Sao Paulo State Univ, Sch Sci & Technol, Dept Phys Educ, Skeletal Muscle Assessment Lab, Presidente Prudente - Brazil

^[3] Fed Univ Maranhao UFMA, Dept Phys Educ, Lab Cellular & Mol Biol Skeletal Muscle LABCEMME, Sao Luis - Brazil

^[4] Coastal Carolina Univ, Dept Kinesiol, Conway, SC - USA

• Tipo de documento: Artigo de Revisão
• Fonte: FRONTIERS IN PHYSIOLOGY; v. 9, OCT 9 2018.
• Citações Web of Science: 1

Resumo

Blood flow restriction (BFR) combined with low-intensity strength training has been shown to increase skeletal muscle mass and strength in a variety of populations. BFR results in a robust metabolic stress which is hypothesized to induce muscle growth via increased recruitment of fast-twitch muscle fibers, a greater endocrine response, and/or enhancing the cellular swelling contribution to the hypertrophic process. Following exercise, neutrophils are the first immune cells to initiate the tissue remodeling process via several mechanisms including an increased production of cytokines and recruitment of monocytes/macrophages, which facilitate the phagocytosis of foreign particles, the differentiation of myoblasts, and the formation of new myotubes. Thus, the purpose of this review was to discuss the mechanisms through which metabolic stress and immune cell recruitment may induce skeletal muscle remodeling following BFR strength training. (AU)

• Processo FAPESP: 15/23910-8 - Remodelamento da musculatura esquelética induzida por restrição de fluxo sanguíneo e treinamento de força de baixa intensidade: o papel do recrutamento de neutrófilos/macrófagos
• Beneficiário: Fabrício Eduardo Rossi
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 16/16712-8 - Envolvimento do BDNF na função de linfócitos de indivíduos obesos sedentários e treinados: relação com aspectos cognitivos
• Beneficiário: Fábio Santos de Lira
• Modalidade de apoio: Auxílio à Pesquisa - Regular