Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Lack of serological and molecular evidence of arbovirus infections in bats from Brazil

Texto completo
Autor(es):
Bittar, Cintia [1] ; Machado, Rafael R. G. [1] ; Comelis, Manuela T. [2] ; Bueno, Larissa M. [2] ; Morielle-Versute, Eliana [2] ; Beguelini, Matheus R. [2, 3] ; de Souza, Renato P. [4] ; Nogueira, Mauricio L. [5] ; Rahal, Paula [1]
Número total de Autores: 9
Afiliação do(s) autor(es):
[1] Univ Estadual Paulista, UNESP, Inst Biociencias Letras & Ciencias Exatas, Lab Estudos Genom, Sao Jose Do Rio Preto, SP - Brazil
[2] Univ Estadual Paulista, Lab Chiroptera, Inst Biociencias Letras & Ciencias Exatas, Sao Jose Do Rio Preto, SP - Brazil
[3] UFOB, Ctr Ciencias Biol & Saude, Barreiras, BA - Brazil
[4] Adolfo Lutz Inst, Nucleo Doencas Transmissao Vetorial, Sao Paulo - Brazil
[5] FAMERP Fac Med Sao Jose do Rio Preto, Lab Pesquisa Virol, Sao Jose Do Rio Preto, SP - Brazil
Número total de Afiliações: 5
Tipo de documento: Artigo Científico
Fonte: PLoS One; v. 13, n. 11 NOV 7 2018.
Citações Web of Science: 1
Resumo

Viruses are important agents of emerging zoonoses and are a substantial public health issue. Among emerging viruses, an important group are arboviruses, which are characterized by being maintained in nature in cycles involving hematophagous arthropod vectors and a wide range of vertebrate hosts. Recently, bats have received increasing attention as an important source for the emergence of zoonoses and as possible viral reservoirs. Among the arboviruses, there are many representatives of the genera Fla vi virus and Alpha virus, which are responsible for important epidemics such as Dengue virus, Zika virus and Chikungunya virus. Due to the importance of analyzing potential viral reservoirs for zoonosis control and expanding our knowledge of bat viruses, this study aimed to investigate the presence of viruses of the Alpha virus and Fla vi virus genera in bats. We analyzed serum, liver, lungs and intestine from 103 bats sampled in northeast and southern Brazil via Nested-PCR and the hemagglutination inhibition test. All samples tested in this study were negative for arboviruses, suggesting that no active or past infection was present in the captured bats. These data indicate that the bats examined herein probably do not constitute a reservoir for these viruses in the studied areas. Further studies are needed to clarify the role of bats as reservoirs and sources of infection of these viral zoonoses. (AU)

Processo FAPESP: 15/09704-6 - Investigação de arbovírus em Chiroptera
Beneficiário:Rafael Rahal Guaragna Machado
Modalidade de apoio: Bolsas no Brasil - Iniciação Científica