Autor(es):Mostrar menos -

Sato, Joao Ricardo ^{[1, 2, 3, 4]} ; Biazoli Jr, Claudinei Eduardo ; Moura, Luciana Monteiro ^{[1, 5]} ; Crossley, Nicolas ^{[6, 7, 8]} ; Zugman, Andre ^{[1, 3]} ; Picon, Felipe Almeida ^{[9, 1, 10]} ; Hoexter, Marcelo Queiroz ^{[1, 11, 3]} ; Amaro Jr, Edson ; Miguel, Euripedes Constantino ^{[1, 11]} ; Rohde, Luis Augusto ^{[9, 1, 10]} ; Bressan, Rodrigo Affonseca ^{[1, 3]} ; Jackowski, Andrea Parolin ^{[1, 3]}

Afiliação do(s) autor(es):Mostrar menos -

^[1] CNPq, Natl Inst Dev Psychiat Children & Adolescents, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Sch Med, Dept Radiol, Sao Paulo - Brazil

^[3] Univ Fed Sao Paulo UNIEESP, Interdisciplinary Lab Clin Neurosci LiNC, Dept Psychiat, Sao Paulo - Brazil

^[4] Univ Fed ABC, Ctr Math Comp & Cognit, Ave Estados 5001, BR-09210580 Santo Andre, SP - Brazil

^[5] Biazoli Jr, Jr., Claudinei Eduardo, Univ Fed ABC, Ctr Math Comp & Cognit, Ave Estados 5001, BR-09210580 Santo Andre, SP - Brazil

^[6] P Catholic Univ Chile, Inst Biol & Med Engn, Fac Engn, Santiago - Chile

^[7] P Catholic Univ Chile, Inst Biol & Med Engn, Fac Med, Santiago - Chile

^[8] P Catholic Univ Chile, Inst Biol & Med Engn, Fac Biol Sci, Santiago - Chile

^[9] Univ Fed Rio Grande do Sul, Dept Psychiat, Porto Alegre, RS - Brazil

^[10] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Dept Psychiat, Porto Alegre, RS - Brazil

^[11] Univ Sao Paulo, Fac Med FMUSP, Dept Psychiat, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: BRAIN CONNECTIVITY; v. 9, n. 5, p. 379-387, JUN 1 2019.
• Citações Web of Science: 0

Resumo

The fractional amplitude of low-frequency fluctuations (fALFFs) of the BOLD signal have been successfully applied as exploratory tools in neuroimaging. This metric has been useful in mapping brain functional changes in many clinical populations. However, little is known about the neurophysiological correlates of fALFF. This study aimed at demonstrating that fALFF is related to local network centrality during childhood and adolescence. The establishment of this relationship is fundamental to provide a more meaningful explanation to previous clinical and neurodevelopmental studies based on fALFF. Our findings show a correlation of similar to 0.5 between these two metrics at a group level, which is a finding replicated in four large independent samples. However, when considering the across-subject and intra-subject correlations between the two metrics, the correlation is much lower, probably due to the low signal-to-noise ratio. Moreover, we found that regions with high fALFF and degree centrality overlapped modestly, particularly the posterior cingulate/precuneus and lateral parietal cortices. (AU)

• Processo FAPESP: 16/04983-7 - Neuroimagem, genômica, transcriptômica e epigenômica: conduzindo análises em larga escala em direção a um modelo integrativo de transtornos mentais
• Beneficiário: Jair de Jesus Mari
• Modalidade de apoio: Auxílio à Pesquisa - Programa eScience e Data Science - Regular
• Processo FAPESP: 13/08531-5 - Coorte de alto risco para transtornos psiquiátricos na infância: seguimento de neuroimagem após 3 anos
• Beneficiário: Andrea Parolin Jackowski
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 18/21934-5 - Estatística de redes: teoria, métodos e aplicações
• Beneficiário: André Fujita
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 14/50917-0 - INCT 2014: psiquiatria do desenvolvimento para crianças e adolescentes
• Beneficiário: Eurípedes Constantino Miguel Filho
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 18/04654-9 - Séries temporais, ondaletas e dados de alta dimensão
• Beneficiário: Pedro Alberto Morettin
• Modalidade de apoio: Auxílio à Pesquisa - Temático