Neuroendocrine Control, Inflammation, and Psychological Aspects After Interdisciplinary Therapy in Obese Women

Autor(es)

Moraes, Amanda dos Santos ^{[1, 2]} ; Taddeo Cipullo, Marcos Alberto ^{[1, 3]} ; Schoenardie Poli, Vanessa Fadanelli ^{[1, 2]} ; Rebelo, Renata Astride ^[1] ; Ribeiro, Eliane Beraldi ^{[1, 4]} ; Oyama, Lila Missae ^{[1, 4]} ; Andrade Silva, Stephan Garcia ^{[1, 2]} ; Damaso, Ana Raimunda ^{[1, 4]} ; Padovani, Ricardo da Costa ^{[1, 3]} ; Caranti, Danielle Arisa ^{[1, 4, 2, 5]}

Afiliação do(s) autor(es)

^[1] Fed Univ Sao Paulo UNIFESP Santos, Obes Study Grp GEO, Sao Paulo, SP - Brazil

^[2] Fed Univ Sao Paulo UNIFESP Santos, Post Grad Program Interdisciplinary Hlth Sci, Sao Paulo, SP - Brazil

^[3] Fed Univ Sao Paulo UNIFESP Santos, Hlth Educ & Soc Dept, Sao Paulo, SP - Brazil

^[4] Fed Univ Sao Paulo UNIFESP Santos, Nutr, Post Grad Program Food, Sao Paulo, SP - Brazil

^[5] Fed Univ Sao Paulo UNIFESP Santos, Biosci Dept, Sao Paulo, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Hormone and Metabolic Research; v. 51, n. 6, p. 375-380, JUN 2019.
• Citações Web of Science: 0

Resumo

Obesity is a chronic and multifactorial disease promoted by positive energy balance. The objective was to evaluate the effects of interdisciplinary therapy in the neuroendocrine control of food intake, inflammatory markers, and psychological aspects in obese women. Forty-seven obese women (43.32 +/- 5.82 years, 34.86 +/- 3.08kg/m (2) ), aged 30-50 years, participated in an interdisciplinary lifestyle change therapy, consisting of nutritional counseling, physical exercises, and psychological therapy for 36 weeks. After the long-term therapy, there was a decrease in body weight (Delta -5.36kg), BMI (Delta -2.01kg/m (2) ), abdominal (Delta -9.09cm), hip (Delta -5.03cm), and thigh (Delta -5.07cm) perimeters. There was also a significant improvement in body composition, with an increase in fat-free mass (Delta 1.60%) and reduction of body fat (Delta -3.74kg). The therapy proposed also provided an improvement in depression scores (Delta -6.63), anxiety (Delta -4.07), body image (Delta -25.25), and binge eating (Delta -5.25). There was a significant reduction in serum levels of leptin (Delta -15.62ng/ml). The interdisciplinary therapy was able to provide both, physical and psychological benefits in energy balance, which enables the use of this model as a feasible clinical strategy for the treatment of obesity. (AU)

• Processo FAPESP: 11/51723-7 - Efeitos da terapia interdisciplinar no controle da síndrome metabólica em adultos obesos e sua relação com as adipocitinas pró- e antiinflamatórias
• Beneficiário: Danielle Arisa Caranti
• Modalidade de apoio: Auxílio à Pesquisa - Regular